SCHEMBL18565494

SCHEMBL18565494

Cn1c2ccc(-c3ccc4c(c3)[Si](C)(C)c3ccccc3-4)cc2c2c3ccccc3c3ccccc3c21

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.33
IDO1 P14902 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
FTO Q9C0B1 1/20 0.33
KDM4E B2RXH2 2/20 0.32
MAPT P10636 1/20 0.32
RET P07949 1/20 0.31
RORA P35398 1/20 0.30
RORC P51449 1/20 0.30
HSD17B10 Q99714 2/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565487 0.90 MAOB (0.36) HSP90AA1IDO1ALKBH5FTOKDM4E
SCHEMBL18565491 0.85 HSP90AA1 (0.31) HSP90AA1IDO1ALKBH5FTOKDM4E
SCHEMBL18565493 0.84 ALKBH5 (0.35) HSP90AA1IDO1ALKBH5FTOKDM4E
SCHEMBL18565492 0.84 RORA (0.31) RORARORC
SCHEMBL18565388 0.83 GPR3 (0.44) HSP90AA1IDO1KDM4EMAPTRORA
SCHEMBL18565461 0.82 KMT2A (0.33) KDM4EMAPTHSD17B10ALDH1A1GAA
SCHEMBL18565381 0.81 ALKBH5 (0.44) HSP90AA1IDO1ALKBH5FTOKDM4E
SCHEMBL23348107 0.79 MAOB (0.44) ALKBH5FTOKDM4EMAPTHSD17B10
SCHEMBL18565384 0.78 RXRA (0.47) HSP90AA1IDO1KDM4EMAPTHSD17B10
SCHEMBL18565423 0.78 LMNA (0.35) KDM4EMAPTRORARORCHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 HSP90AA1 4595/4885IDO1 1153/4885ALKBH5 265/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 HSP90AA1 4595/4885IDO1 1153/4885ALKBH5 265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.