Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13074524 | 0.83 | HCAR2 (0.37) | PIM1PIK3CGCYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL13047439 | 0.80 | PIK3CG (0.34) | PIK3CGCYP11B2CYP11B1POLQHSD17B1 | |
| SCHEMBL13047437 | 0.80 | ABL1 (0.35) | PIK3CGCYP11B2CYP11B1POLQHSD17B1 | |
| SCHEMBL290377 | 0.80 | CYP11B2 (0.35) | PIM1PIK3CGCYP11B2CYP11B1POLQ | |
| SCHEMBL17488376 | 0.78 | PIM1 (0.40) | PIM1PIK3CGCYP11B2CYP11B1POLQ | |
| SCHEMBL13048000 | 0.77 | PAX8 (0.37) | PIK3CGCYP11B2ALDH1A1POLQHSD17B1 | |
| SCHEMBL17589754 | 0.77 | CYP11B2 (0.33) | PIM1PIK3CGCYP11B2CYP11B1POLQ | |
| SCHEMBL290098 | 0.77 | CDC7 (0.40) | PIK3CGPOLQTLR7 | |
| SCHEMBL290654 | 0.76 | ABL1 (0.35) | PIK3CGCYP11B2POLQHSD17B1HSD17B2 | |
| SCHEMBL17589854 | 0.75 | HSD17B1 (0.32) | PIK3CGPOLQHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614826-B1 | Process for preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |