Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29242785 | 0.77 | ALOX15 (0.53) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL5608474 | 0.77 | HDAC8 (0.59) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL23609342 | 0.76 | LMNA (0.46) | ADORA1ADORA2AMEN1KMT2ANPC1 | |
| SCHEMBL2361893 | 0.74 | KDM4E (0.59) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL28344648 | 0.74 | MAPT (0.58) | ADORA1ADORA2AMEN1KMT2ANPC1 | |
| SCHEMBL23783923 | 0.73 | HDAC7 (0.45) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL25876784 | 0.73 | KDM4E (0.53) | ADORA1ADORA2AMEN1KMT2ANPC1 | |
| SCHEMBL1341748 | 0.72 | KDM4E (0.56) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL11847765 | 0.72 | ALDH1A1 (0.46) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL3673876 | 0.72 | ALDH1A1 (0.38) | NPC1RAB9AKDM4EMAPTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1632477-B1 | BENZAMIDE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2017-03-01 | — | — | EP | disclosed |