Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1347714 | 0.80 | FAAH (0.50) | — | |
| SCHEMBL10437615 | 0.79 | MAPT (0.49) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL11346034 | 0.79 | RAB9A (0.59) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL3676959 | 0.77 | RAB9A (0.49) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL16302352 | 0.77 | RAB9A (0.58) | LMNASMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL18569178 | 0.76 | ADORA1 (0.48) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL4486171 | 0.76 | ALDH1A1 (0.56) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL30514611 | 0.75 | MAPT (0.44) | LMNASMN1; SMN2KDM4EIDO1ALDH1A1 | |
| SCHEMBL17046021 | 0.75 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL30910148 | 0.74 | KDM4E (0.46) | LMNASMN1; SMN2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |