Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 10/20 | 0.33 |
| ▸ | CA9 | Q16790 | 10/20 | 0.33 |
| ▸ | CA1 | P00915 | 9/20 | 0.33 |
| ▸ | CA12 | O43570 | 5/20 | 0.33 |
| ▸ | CA4 | P22748 | 5/20 | 0.33 |
| ▸ | CA5A | P35218 | 4/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31736165 | 0.75 | LMNA (0.38) | CA2CA9CA1CA12CA4 | |
| SCHEMBL13826164 | 0.70 | CA2 (0.46) | CHRNA7CA2CA9CA1CA12 | |
| SCHEMBL587813 | 0.69 | KDM4E (0.34) | — | |
| SCHEMBL20610117 | 0.68 | CA2 (0.44) | CA2CA9CA1CA12CA4 | |
| SCHEMBL13386461 | 0.67 | PTGS2 (0.34) | PTGS1PTGS2 | |
| SCHEMBL26597129 | 0.66 | CA2 (0.46) | CA2CA9CA1CA12CA4 | |
| SCHEMBL24221423 | 0.65 | CA2 (0.47) | CA2CA9CA1CA12CA4 | |
| SCHEMBL20610218 | 0.65 | CA1 (0.45) | CA2CA9CA1CA12CA4 | |
| SCHEMBL578844 | 0.65 | APLNR (0.44) | CHRNA7CA2CA9CA1CA12 | |
| SCHEMBL25270597 | 0.63 | GABRP (0.43) | CA2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593108-B2 | Compounds and methods for antiviral treatment | PTC THERAPEUTICS, INC. (US) | 2017-03-14 | — | — | US | disclosed |