Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20341607 | 0.78 | GPR84 (0.44) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL6432284 | 0.77 | CA2 (0.39) | SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL3472515 | 0.77 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL1239842 | 0.77 | GPR84 (0.41) | ZDHHC7GPR84FFAR1MAPTLCK | |
| SCHEMBL14504414 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16699711 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2860007 | 0.70 | FAAH (0.47) | FFAR1MAPTFAAHPPARDMEN1 | |
| SCHEMBL1240747 | 0.70 | FAAH (0.47) | FFAR1MAPTFAAHPPARDMEN1 | |
| SCHEMBL14576719 | 0.70 | CA2 (0.36) | GPR84FFAR1MEN1KMT2A | |
| SCHEMBL19701698 | 0.67 | ALDH1A1 (0.40) | SMN1; SMN2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586931-B2 | Triazolyl derivatives as Syk inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-03-07 | — | — | US | disclosed |