SCHEMBL1859632

SCHEMBL1859632

Fc1ccc2c(c1)OCCN2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP6 P51161 1/20 0.56
ALDH1A1 P00352 2/20 0.49
GAA P10253 2/20 0.49
HSD17B10 Q99714 2/20 0.49
MAPT P10636 2/20 0.49
PIK3CA P42336 1/20 0.41
AR P10275 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GLA P06280 1/20 0.39
HPGD P15428 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
ATM Q13315 1/20 0.39
NR3C1 P04150 1/20 0.38
NR3C2 P08235 1/20 0.38
TRPV1 Q8NER1 1/20 0.38
HDAC11 Q96DB2 1/20 0.37
KMT2A Q03164 1/20 0.37
EGFR P00533 1/20 0.36
ADRA2A P08913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30054665 1.00 FABP6 (0.56) FABP6ALDH1A1GAAHSD17B10MAPT
SCHEMBL17927862 0.89 FABP6 (0.45) FABP6ALDH1A1GAAHSD17B10MAPT
SCHEMBL29429213 0.89 FABP6 (0.45) FABP6ALDH1A1GAAHSD17B10MAPT
SCHEMBL2599652 0.85 ALDH1A1 (0.62) FABP6ALDH1A1GAAHSD17B10MAPT
SCHEMBL29469482 0.85 ALDH1A1 (0.62) FABP6ALDH1A1GAAHSD17B10MAPT
Hydrochloric Acid SCHEMBL2360497 0.83 ALDH1A1 (0.61) FABP6ALDH1A1GAAHSD17B10MAPT
SCHEMBL24820913 0.77 ALDH1A1 (0.49) FABP6ALDH1A1GAAHSD17B10MAPT
SCHEMBL17581725 0.77 ALDH1A1 (0.49) FABP6ALDH1A1GAAHSD17B10MAPT
SCHEMBL303218 0.77 ALDH1A1 (0.49) FABP6ALDH1A1GAAHSD17B10MAPT
SCHEMBL2746377 0.77 ALDH1A1 (0.49) FABP6ALDH1A1GAAHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024170772-A1 EPIGALLOCATECHIN-3-GALLATE (EGCG) ANALOGS FOR USE IN THE TREATMENT OF DISEASES IN WHICH AN INCREASE OF NAD+ IS BENEFICIAL SUCH AS GLAUCOMA MIM NEUROSCIENCES AB (SE) 2024-08-22 WO claimed
WO-2014122674-A1 PROCESS FOR PREPARATION OF DERIVATIVES OF TETRAHYDROPHTHALIMIDE RALLIS INDIA LIMITED (IN) 2014-08-14 WO claimed
US-12624024-B2 EP2 antagonist compounds RESERVOIR NEUROSCIENCE, INC. (US) 2026-05-12 US disclosed
EP-4729508-A1 TETRALIN AND TETRAHYDROQUINOLINE COMPOUNDS AS INHIBITORS OF HIF-2ALPHA Arcus Biosciences, Inc. (US) 2026-04-22 EP disclosed
EP-4695244-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-4692071-A1 PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS TOKUYAMA CORPORATION (JP) 2026-02-11 EP disclosed
EP-4634162-A1 BENZIMIDAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-10-22 EP disclosed
US-20250214930-A1 TETRALIN AND TETRAHYDROQUINOLINE COMPOUNDS AS INHIBITORS OF HIF-2ALPHA ARCUS BIOSCIENCES, INC. (US) 2025-07-03 US disclosed
WO-2025028365-A1 PHOTOCHROMIC COMPOUND, PHENOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS 株式会社トクヤマ 2025-02-06 WO disclosed
US-12157726-B2 P-phenylenediamine derivative as potassium channel regulator and preparation method and medical application thereof SHANGHAI ZHIMENG BIOPHARMA INC. 2024-12-03 US disclosed
WO-2024213650-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-10-17 WO disclosed
US-7365064-B2 Benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them DR. REDDY'S LABORATORIES LIMITED (IN) 2008-04-29 US disclosed
US-20060100202-A1 Novel compounds SMITHKLINE BEECHAM PLC (GB) 2006-05-11 US disclosed
US-20050113368-A1 Benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them DR. REDDY'S LABORATORIES LIMITED (IN) 2005-05-26 US disclosed
EP-1474403-A2 UREA DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 2004-11-10 EP disclosed
EP-1436247-A1 NOVEL-BETA-PHENYL-ALPHA-OXYSUBSTITUTED PROPIONIC DERIVATIVES: PROCESS FOR ITS PREPARATION AND THEIR USE IN THE PREPARATION OF PHARMACEUTICALLY IMPORTANT COMPOUNDS Dr. Reddy's Laboratories Ltd. (IN) 2004-07-14 EP disclosed
EP-1436268-A1 BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Dr. Reddy's Laboratories Ltd. (IN) 2004-07-14 EP disclosed
WO-2003053945-A2 UREA DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM P.L.C. (GB) 2003-07-03 WO disclosed
WO-2003033481-A1 BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND PARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S LABORATORIES LTD. (IN) 2003-04-24 WO disclosed
WO-2003033456-A1 NOVEL β-PHENYL-α-OXYSUBSTITUTED PROPIONIC DERIVATIVES: PROCESS FOR ITS PREPARATION AND THEIR USE IN THE PREPARATION OF PHARMACEUTICALLY IMPORTANT COMPOUNDS DR. REDDY'S LABORATORIES LTD. (IN) 2003-04-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12157726-B2 P-phenylenediamine derivative as potassium channel regulator and preparation method and medical application thereof KCNJ2, KCNN2, KCNH2 FABP6 2073/4885ALDH1A1 1733/4885GAA 3200/4885
US-20250214930-A1 TETRALIN AND TETRAHYDROQUINOLINE COMPOUNDS AS INHIBITORS OF HIF-2ALPHA HIF1AN, HIF1A, EGLN2 FABP6 2730/4885ALDH1A1 2241/4885GAA 1620/4885
US-20050113368-A1 Benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them CYP3A5, HBZ, CYP4Z1 FABP6 809/4885ALDH1A1 1644/4885GAA 333/4885
US-12624024-B2 EP2 antagonist compounds PTGER1, PTGER2, PTGER4 FABP6 1167/4885ALDH1A1 1286/4885GAA 4863/4885
US-20060100202-A1 Novel compounds F12, REN, AVPR2 FABP6 816/4885ALDH1A1 1317/4885GAA 1602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.