Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1862185 | 0.79 | CYP1A2 (0.41) | TAAR1MAPT | |
| SCHEMBL1862209 | 0.79 | IDO1 (0.46) | TAAR1SLC6A2SLC6A4SLC6A3LTA4H | |
| SCHEMBL1861221 | 0.77 | KDM4E (0.44) | LTA4HARPOLBKDM4E | |
| SCHEMBL1857797 | 0.75 | CALM1 (0.55) | LTA4HLMNA | |
| SCHEMBL1859749 | 0.74 | TAAR1 (0.37) | TAAR1TYMPNPC1RAB9ALTA4H | |
| SCHEMBL8095627 | 0.74 | LTA4H (0.53) | TAAR1SLC6A2SLC6A4SLC6A3LTA4H | |
| SCHEMBL11303064 | 0.74 | MAPK1 (0.47) | TAAR1SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL29477327 | 0.73 | TAAR1 (0.56) | TAAR1TYMPLTA4HARCHRM2 | |
| SCHEMBL2090458 | 0.73 | TAAR1 (0.56) | TAAR1TYMPLTA4HARCHRM2 | |
| SCHEMBL1859758 | 0.72 | SRD5A2 (0.39) | TAAR1NPC1RAB9ALTA4HMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939509-B2 | Partial and full agonists of A1 adenosine receptors | GILEAD SCIENCES, INC. (US) | 2011-05-10 | — | — | US | disclosed |