SCHEMBL7469332

SCHEMBL7469332

CCN(CC)CCNC(=O)C1CCCCC1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.66
TSHR P16473 1/20 0.66
KMT2A Q03164 3/20 0.62
NAAA Q02083 1/20 0.58
LMNA P02545 1/20 0.54
EPHX1 P07099 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.47
HSD17B10 Q99714 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
ALDH1A1 P00352 1/20 0.46
STAT3 P40763 1/20 0.45
MEN1 O00255 2/20 0.44
KEAP1 Q14145 1/20 0.44
NFE2L2 Q16236 1/20 0.44
NPC1 O15118 1/20 0.43
PKM P14618 1/20 0.43
EPHX2 P34913 1/20 0.43
RAB9A P51151 1/20 0.43
TP53 P04637 1/20 0.43
THRB P10828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21974696 0.90 LMNA (0.66) POLBTSHRKMT2ANAAALMNA
SCHEMBL9795281 0.85 TSHR (0.57) POLBTSHRKMT2ANAAALMNA
SCHEMBL9795287 0.85 TSHR (0.57) POLBTSHRKMT2ANAAALMNA
SCHEMBL2325837 0.83 GNAI3 (0.59) POLBTSHRKMT2ANAAALMNA
SCHEMBL7260975 0.82 NAAA (0.57) POLBTSHRKMT2ANAAAEPHX1
SCHEMBL25027395 0.82 NAAA (0.54) POLBTSHRKMT2ANAAALMNA
Oxalic Acid SCHEMBL9795105 0.81 POLB (0.53) POLBTSHRKMT2ANAAALMNA
SCHEMBL12820426 0.81 POLB (0.53) POLBTSHRKMT2ANAAALMNA
Oxalic Acid SCHEMBL9795121 0.81 POLB (0.53) POLBTSHRKMT2ANAAALMNA
Hydrochloric Acid SCHEMBL21198744 0.81 NAAA (0.56) POLBTSHRKMT2ANAAAEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3922267-A1 PEGYLATED RECOMBINANT HUMAN GROWTH HORMONE COMPOUNDS ASCENDIS PHARMA ENDOCRINOLOGY DIVISION A/S (DK) 2021-12-15 EP disclosed
EP-2459220-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2020-09-09 EP disclosed
EP-2237799-B1 PRODRUG COMPRISING A SELF-CLEAVABLE LINKER ASCENDIS PHARMA AS (DK) 2019-04-10 EP disclosed
EP-0693070-B1 PYRIDO[2,3-b](1,4)BENZODIAZEPINONES AS M2 RECEPTOR LIGAND FOR THE TREATMENT OF NEUROLOGICAL DISORDERS PHARMACEUTICAL DISCOVERY CORP (US) 2002-07-24 EP disclosed
EP-1120416-A1 Pyrido[2.3-b][1,4]benzodiazepinones as M2 receptor ligand for the treatment of neurological disorders PHARMACEUTICAL DISCOVERY CORPORATION (US) 2001-08-01 EP disclosed
EP-0693070-A1 PYRIDO 2,3-b] 1,4]BENZODIAZEPINONES AS M 2? RECEPTOR LIGAND FOR THE TREATMENT OF NEUROLOGICAL DISORDERS PHARMACEUTICAL DISCOVERY CORPORATION (US) 1996-01-24 EP disclosed
WO-1994022861-A1 PYRIDO[2,3-b][1,4]BENZODIAZEPINONES AS M2 RECEPTOR LIGAND FOR THE TREATMENT OF NEUROLOGICAL DISORDERS PHARMACEUTICAL DISCOVERY CORPORATION (US) 1994-10-13 WO disclosed