Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795287 | 1.00 | TSHR (0.57) | TSHRPOLBLMNAKMT2ASIGMAR1 | |
| Oxalic Acid SCHEMBL9795121 | 0.95 | POLB (0.53) | TSHRPOLBLMNAKMT2ASIGMAR1 | |
| Oxalic Acid SCHEMBL9795105 | 0.95 | POLB (0.53) | TSHRPOLBLMNAKMT2ASIGMAR1 | |
| SCHEMBL7469332 | 0.85 | POLB (0.66) | TSHRPOLBLMNAKMT2ASIGMAR1 | |
| SCHEMBL9795296 | 0.83 | HSD11B1 (0.49) | TSHRPOLBLMNAKMT2ATP53 | |
| SCHEMBL12820426 | 0.83 | POLB (0.53) | TSHRPOLBLMNAKMT2ASIGMAR1 | |
| SCHEMBL2325837 | 0.82 | GNAI3 (0.59) | TSHRPOLBLMNAKMT2ASIGMAR1 | |
| SCHEMBL9795115 | 0.81 | TSHR (0.52) | TSHRPOLBLMNAKMT2ASIGMAR1 | |
| SCHEMBL20928274 | 0.80 | NAAA (0.51) | KMT2ANAAASMN1; SMN2GNAI3GNAO1 | |
| SCHEMBL9795239 | 0.77 | POLB (0.48) | TSHRPOLBLMNAKMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |