Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3113946 | 0.78 | ACHE (0.32) | ACHEHSD17B10TSHR | |
| SCHEMBL18603 | 0.76 | ALDH1A1 (0.43) | ACHEHSD17B10TSHRTDP1ALDH1A1 | |
| SCHEMBL6047839 | 0.74 | MEN1 (0.34) | ALDH1A1LMNA | |
| SCHEMBL2684523 | 0.74 | ATM (0.41) | TSHRCYP3A4TDP1ALDH1A1FBP1 | |
| SCHEMBL2441755 | 0.74 | ALDH1A1 (0.36) | TSHRCYP3A4PKMTDP1ALDH1A1 | |
| SCHEMBL2040645 | 0.74 | MAPK1 (0.41) | HSD17B10TSHRPKMTDP1ALDH1A1 | |
| SCHEMBL6047845 | 0.74 | TDP1 (0.32) | TDP1ALDH1A1LMNA | |
| SCHEMBL1921008 | 0.74 | ALDH1A1 (0.46) | HSD17B10TSHRCYP3A4PKMTDP1 | |
| SCHEMBL6645369 | 0.74 | MAPT (0.43) | ACHEHSD17B10TSHRALDH1A1LMNA | |
| SCHEMBL2681882 | 0.74 | FBP1 (0.41) | PKMALDH1A1FBP1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575587-A1 | IMINOSUGAR DERIVATIVES AS GLUCOSIDASE INHIBITORS | RANBAXY LABORATORIES, LTD. (IN) | 2005-09-21 | — | — | EP | claimed |
| US-6888022-B2 | Methods and compounds for inhibiting β-amyloid peptide release and/or its synthesis | ATHENA NEUROSCIENCES, INC. (US) | 2005-05-03 | — | — | US | claimed |
| WO-2004039373-A1 | IMINOSUGAR DERIVATIVES AS GLUCOSIDASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2004-05-13 | — | — | WO | claimed |
| US-6677452-B1 | PREPARED BY REACTING AMINE WITH PYRIDINE SUBSTITUTED WITH HALOGEN AT POSITION 6 AND WITH CARBOXY OR SULFONYL GROUP AT ANOTHER POSITION TO FORM AMIDE OR SULFONAMIDE, DISPLACING HALOGEN WITH DESIRED DIAMINE | LION BIOSCIENCE AG (DE) | 2004-01-13 | — | — | US | claimed |
| EP-1218343-A4 | PYRIDINE CARBOXAMIDE OR SULFONAMIDE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2003-06-18 | — | — | EP | claimed |
| EP-1218343-A1 | PYRIDINE CARBOXAMIDE OR SULFONAMIDE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-07-03 | — | — | EP | claimed |
| WO-2001025203-A1 | PYRIDINE CARBOXAMIDE OR SULFONAMIDE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-04-12 | — | — | WO | claimed |
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | claimed |
| EP-0286746-B1 | INSECTICIDAL N-(OPTIONALLY SUBSTITUTED) - N'-SUBSTITUTED-N,N'-DISUBSTITUTED- HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | claimed |
| EP-0286746-A1 | Insecticidal N-(optionally substituted) - N'-substituted-N,N'-disubstituted- hydrazines | ROHM AND HAAS COMPANY (US) | 1988-10-19 | — | — | EP | claimed |
| WO-2024037851-A1 | USE OF ADDITIVES FOR IMPROVING THE PROCESSING OF POLYETHYLENES | BASF SE (DE) | 2024-02-22 | — | — | WO | disclosed |
| US-20230190717-A1 | P38 GAMMA INHIBITORS AND METHOD OF USE THEREOF | CITY OF HOPE | 2023-06-22 | — | — | US | disclosed |
| CN-116217548-A | Amide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-109071458-B | Triamide compounds and compositions comprising the same | 美利肯公司 | 2021-12-10 | — | — | CN | disclosed |
| WO-2021145521-A1 | PYRIDO[3,4-D]PYRIMIDINE DERIVATIVE AND THERAPEUTIC PHARMACEUTIC COMPOSITION COMPRISING SAME | 한국과학기술연구원 | 2021-07-22 | — | — | WO | disclosed |
| US-4568377-A | IMPROVED CROP SAFETY | CHEVRON RESEARCH COMPANY (US) | 1986-02-04 | — | — | US | disclosed |
| WO-1986000527-A1 | CELL-DELIVERY AGENT | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1986-01-30 | — | — | WO | disclosed |
| US-4537623-A | Herbicidal 2-(oxa or thia heterocycle)5-amino-3-oxo-4-(substituted-phenyl)-2,3-dihydrofurans | CHEVRON RESEARCH COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0057565-A1 | Beta-lactam antibiotics, their preparation and use | BEECHAM GROUP PLC (GB) | 1982-08-11 | — | — | EP | disclosed |
| US-4137273-A | INSECTICIDES, CHEMICAL INTERMEDIATES | ZOECON CORPORATION (US) | 1979-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190717-A1 | P38 GAMMA INHIBITORS AND METHOD OF USE THEREOF | CDC42BPG, MAPK1, MAPK7 | ACHE 4834/4885HSD17B10 2609/4885TSHR 3124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.