SCHEMBL1860425

SCHEMBL1860425

CS(=O)(=O)Oc1ccc(C(=O)C2C(=O)CCCC2=O)c([N+](=O)[O-])c1

nearest known ligand 0.71

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HPD P32754 2/20 0.58
MEN1 O00255 1/20 0.39
PKM P14618 1/20 0.39
KMT2A Q03164 1/20 0.39
ENPP3 O14638 1/20 0.34
ENPP1 P22413 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30177033 1.00 HPD (0.58) HPDMEN1PKMKMT2AENPP3
SCHEMBL997958 0.83 HPD (0.39) HPDMEN1KMT2A
SCHEMBL998546 0.83 HPD (0.39) HPDMEN1PKMKMT2AENPP3
Mesotrione SCHEMBL29352201 0.83 HPD (0.62) HPDMEN1PKMKMT2A
Mesotrione SCHEMBL4895947 0.83 HPD (0.62) HPDMEN1PKMKMT2A
Mesotrione SCHEMBL22116 0.83 HPD (0.62) HPDMEN1PKMKMT2A
Mesotrione SCHEMBL2233142 0.82 HPD (0.61) HPDMEN1PKMKMT2A
Mesotrione SCHEMBL20723476 0.82 HPD (0.61) HPDMEN1PKMKMT2A
Mesotrione SCHEMBL1667345 0.82 HPD (0.61) HPDMEN1PKMKMT2A
Mesotrione SCHEMBL1162075 0.82 HPD (0.61) HPDMEN1PKMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140121105-A1 AGROCHEMICAL FORMULATION SYNGENTA CROP PROTECTION, LLC (US) 2014-05-01 US claimed
JP-2011524387-A 2011-09-01 JP claimed
US-20100105556-A1 SUSPOEMULSIONS COMPRISING AN HPPD-INHIBITING AND A CHLORACETAMIDE HERBICIDE SYNGENTA CROP PROTECTION, INC. (US) 2010-04-29 US claimed
WO-2010003499-A2 AGROCHEMICAL FORMULATION SYNGENTA PARTICIPATIONS AG (CH) 2010-01-14 WO claimed
EP-1672982-B1 METHOD OF CONTROLLING WEEDS SYNGENTA PARTICIPATIONS AG (CH) 2008-08-27 EP claimed
EP-1515609-B1 HERBICIDAL COMPOSITION SYNGENTA LTD (GB) 2008-04-23 EP claimed
US-20070293396-A1 Suspoemulsions Comprising an Hppd-Inhibiting and a Chloracetamide Herbicide SYNGENTA CROP PROTECTION, INC. (US) 2007-12-20 US claimed
EP-1603388-B1 HERBICIDAL SUSPOEMULSION SYNGENTA PARTICIPATIONS AG (CH) 2007-05-16 EP claimed
US-20060211578-A1 Method of controlling weeds SYNGENTA CROP PROTECTION, INC. 2006-09-21 US claimed
US-20060183643-A1 AGROCHEMICAL FORMULATION SYNGENTA CROP PROTECTION, INC. 2006-08-17 US claimed
EP-1032267-A1 METHOD OF CONTROLLING WEEDS IN TRANSGENIC CROPS AVENTIS CROPSCIENCE S.A. (FR) 2000-09-06 EP claimed
US-6069115-A BY A SINGLE POST-EMERGENT APPLICATION OF A GLYPHOSATE HERBICIDE, AND A GIVEN DERIVATIVES OF P-HYDROXYPHENYLPYRUVATE DIOXYGENASE(HPPD)-INHIBITING HERBICIDES TO GLYPHOSATE TOLERANT CROPS RHONE-POULENC AGROCHIMIE (FR) 2000-05-30 US claimed
EP-0880317-B1 STABLE HERBICIDAL COMPOSITIONS CONTAINING METAL CHELATES OF HERBICIDAL DIONE COMPOUNDS ZENECA LTD (GB) 2000-01-05 EP claimed
US-5912207-A HEAT STABLE, CHEMICALLY STABLE HERBICIDES ZENECA LIMITED (GB) 1999-06-15 US claimed
WO-1999023886-A1 METHOD OF CONTROLLING WEEDS IN TRANSGENIC CROPS AVENTIS CROPSCIENCE S.A. (FR) 1999-05-20 WO claimed
EP-0756452-B1 SYNERGISTIC HERBICIDAL COMPOSITION AND METHOD OF USE THEREOF ZENECA LTD (GB) 1999-05-12 EP claimed
EP-0880317-A1 STABLE HERBICIDAL COMPOSITIONS CONTAINING METAL CHELATES OF HERBICIDAL DIONE COMPOUNDS ZENECA LIMITED (GB) 1998-12-02 EP claimed
US-5698493-A MIXTURE OF ATRAZINE AND 2-(2'-NITRO-4'-METHYLSULFONYLBENZOYL)-1,3-CYCLOHEXANEDIONE OR THE CORRESPONDING METHYLSULFONYLOXY DERIVATIVE ZENECA LIMITED (GB) 1997-12-16 US claimed
WO-1997027748-A1 STABLE HERBICIDAL COMPOSITIONS CONTAINING METAL CHELATES OF HERBICIDAL DIONE COMPOUNDS ZENECA LIMITED (GB) 1997-08-07 WO claimed
US-5089046-A Herbicides or miticide SANDOZ LTD. (CH) 1992-02-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105556-A1 SUSPOEMULSIONS COMPRISING AN HPPD-INHIBITING AND A CHLORACETAMIDE HERBICIDE HPD, DDT, MPST HPD 1/4885MEN1 4851/4885PKM 909/4885
US-20060183643-A1 AGROCHEMICAL FORMULATION DDT, BOLA2; BOLA2B, CIP2A HPD 529/4885MEN1 4454/4885PKM 2758/4885
US-20140121105-A1 AGROCHEMICAL FORMULATION DDT, CIP2A, BOLA2; BOLA2B HPD 556/4885MEN1 4514/4885PKM 3138/4885
US-20060211578-A1 Method of controlling weeds CA3, HACL2, CA2 HPD 228/4885MEN1 4056/4885PKM 2733/4885
US-20070293396-A1 Suspoemulsions Comprising an Hppd-Inhibiting and a Chloracetamide Herbicide HPD, DDT, MPST HPD 1/4885MEN1 4851/4885PKM 909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.