Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | PPM1B | O75688 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2699295 | 1.00 | CHRM2 (0.42) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL15644597 | 1.00 | CHRM2 (0.42) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL2701193 | 1.00 | CHRM2 (0.42) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL22061911 | 0.90 | CHRM2 (0.47) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL1298159 | 0.89 | CHRM2 (0.48) | CHRM2CHRM4CHRM3CHRNB2CHRNA4 | |
| SCHEMBL8494369 | 0.89 | CHRM2 (0.48) | CHRM2CHRM4CHRM3CHRNB2CHRNA4 | |
| SCHEMBL31285391 | 0.89 | CHRM2 (0.48) | CHRM2CHRM4CHRM3CHRNB2CHRNA4 | |
| SCHEMBL974400 | 0.89 | CHRM2 (0.48) | CHRM2CHRM4CHRM3CHRNB2CHRNA4 | |
| SCHEMBL974399 | 0.89 | CHRM2 (0.48) | CHRM2CHRM4CHRM3CHRNB2CHRNA4 | |
| SCHEMBL974796 | 0.89 | CHRM2 (0.48) | CHRM2CHRM4CHRM3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3894477-B1 | CONTROLLED CURE FOR COMPOSITIONS COMPRISING ACETOACETYLATED RESINS | EASTMAN CHEM CO (US) | 2025-01-15 | — | — | EP | disclosed |
| EP-3894475-B1 | ASSEMBLY COMPONENTS COMPRISING CURABLE COMPOSITIONS CONTAINING ACETOACETYLATED RESINS | EASTMAN CHEM CO (US) | 2024-06-19 | — | — | EP | disclosed |
| EP-3894473-B1 | CURABLE ACETOACETYLATED RESIN COMPOSITIONS AND ADDITIVES COMPRISING ADHESION PROMOTERS, GREEN STRENGTH ENHANCERS, OR COMBINATIONS THEREOF | EASTMAN CHEM CO (US) | 2024-06-12 | — | — | EP | disclosed |
| US-11820923-B2 | Controlled cure for compositions comprising acetoacetylated resins | EASTMAN CHEMICAL COMPANY (US) | 2023-11-21 | — | — | US | disclosed |
| CN-113195633-B | Curable compositions comprising acetoacetylated resin, aldehyde, and certain amines | 伊士曼化工公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-113195635-B | Curable acetoacetylated resin composition and additive comprising adhesion promoter, initial strength enhancer, or combination thereof | 伊士曼化工公司 | 2023-10-10 | — | — | CN | disclosed |
| EP-3894474-B1 | CURABLE COMPOSITIONS COMPRISING ACETOACETYLATED RESINS, ALDEHYDES AND CERTAIN AMINES | EASTMAN CHEM CO (US) | 2023-09-13 | — | — | EP | disclosed |
| CN-113260673-B | Assembly comprising a curable composition comprising an acetoacetylated resin | 伊士曼化工公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-113195632-B | Controlled curing of compositions comprising acetoacetylated resins | 伊士曼化工公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-113195634-B | Flexible substrate comprising curable composition comprising acetoacetylated resin | 伊士曼化工公司 | 2023-06-16 | — | — | CN | disclosed |
| WO-2008119688-A1 | PHOTOACTIVABLE NITROGEN BASES | BASF SE (CH) | 2008-10-09 | — | — | WO | disclosed |
| EP-1796745-A2 | POLYMER-BASED TISSUE-ADHESIVE FOR MEDICAL USE | E.I.Du pont de nemours and company (US) | 2007-06-20 | — | — | EP | disclosed |
| US-20070048337-A1 | Aldol-crosslinked polymeric hydrogel adhesives | ACTAMAX SURGICAL MATERIALS, LLC | 2007-03-01 | — | — | US | disclosed |
| US-20070048251-A1 | Methods for sealing an orifice in tissue using an aldol-crosslinked polymeric hydrogel adhesive | ACTAMAX SURGICAL MATERIALS, LLC | 2007-03-01 | — | — | US | disclosed |
| WO-2006042169-A2 | POLYMER-BASED TISSUE-ADHESIVE FOR MEDICAL USE | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-04-20 | — | — | WO | disclosed |
| US-20060079599-A1 | Polymer-based tissue-adhesive form medical use | ACTAMAX SURGICAL MATERIALS, LLC | 2006-04-13 | — | — | US | disclosed |
| US-5817777-A | SEQUESTERING | AMERSHAM INTERNATIONAL PLC (GB) | 1998-10-06 | — | — | US | disclosed |
| EP-0668855-B1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS FOR USE AS CHELATING AGENTS | AMERSHAM INT PLC (GB) | 1998-06-24 | — | — | EP | disclosed |
| EP-0668855-A1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS FOR USE AS CHELATING AGENTS | AMERSHAM INTERNATIONAL plc (GB) | 1995-08-30 | — | — | EP | disclosed |
| WO-1994011339-A1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS FOR USE AS CHELATING AGENTS | AMERSHAM INTERNATIONAL PLC (GB) | 1994-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079599-A1 | Polymer-based tissue-adhesive form medical use | ADSL, SI, VCAM1 | CHRM2 3663/4885CHRM4 3556/4885CHRM3 3231/4885 |
| US-20070048337-A1 | Aldol-crosslinked polymeric hydrogel adhesives | ALDOA, ADSL, ALDH1A2 | CHRM2 1492/4885CHRM4 1849/4885CHRM3 1519/4885 |
| US-20070048251-A1 | Methods for sealing an orifice in tissue using an aldol-crosslinked polymeric hydrogel adhesive | SI, ADSL, AOX1 | CHRM2 2875/4885CHRM4 2655/4885CHRM3 2301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.