Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.48 |
| ▸ | INPP5B | P32019 | 1/20 | 0.48 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | IDUA | P35475 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20472218 | 0.87 | CXCL8 (0.60) | CXCL8AKR1B1CHRM1CAMK2AFABP4 | |
| SCHEMBL25833590 | 0.84 | L3MBTL1 (0.57) | CXCL8KDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL13182856 | 0.83 | KDM4E (0.53) | CXCL8KDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL18607330 | 0.81 | TSHR (0.49) | KDM4EUSP2ALDH1A1HPGDPDE3A | |
| SCHEMBL22754284 | 0.81 | KDM4E (0.47) | CXCL8KDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL23692351 | 0.80 | ALDH1A1 (0.46) | CXCL8KDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL31530597 | 0.80 | KDM4E (0.50) | KDM4EUSP2ALDH1A1HPGDPDE3A | |
| SCHEMBL8046680 | 0.80 | CXCL8 (0.52) | CXCL8AKR1B1CHRM1CAMK2AFABP4 | |
| SCHEMBL4957570 | 0.79 | INPPL1 (0.53) | KDM4EUSP2ALDH1A1HPGDPDE3A | |
| SCHEMBL29647909 | 0.79 | INPPL1 (0.53) | KDM4EUSP2ALDH1A1HPGDPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018148224-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2018-08-16 | — | — | WO | claimed |
| WO-2025095130-A1 | BATTERY PACK AND SPACER | 三菱ケミカル株式会社 | 2025-05-08 | — | — | WO | disclosed |
| EP-4209483-A1 | PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2023-07-12 | — | — | EP | disclosed |
| US-20210230195-A1 | PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC | 2021-07-29 | — | — | US | disclosed |
| WO-2018148224-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2018-08-16 | — | — | WO | disclosed |
| WO-2017198647-A1 | 6-(BUTA-1,3-DIYN-1-YL)BENZO[D]THIAZOLE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2017-11-23 | — | — | WO | disclosed |
| WO-2017036968-A1 | ANTIBACTERIAL ANNULATED PYRROLIDIN-2-ONE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2017-03-09 | — | — | WO | disclosed |
| WO-2017037039-A1 | ANTIBACTERIAL HETEROCYCLIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2017-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230195-A1 | PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY | ATF4, ATF1, DDIT3 | CXCL8 1866/4885KDM4E 4466/4885USP2 1505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.