SCHEMBL18608404

SCHEMBL18608404

BrCc1ccc(CI)cc1

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzyl Bromide SCHEMBL8527577 0.86 TSHR (0.74) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL649682 0.83 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL131361 0.83 ALDH1A1 (0.67) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL127491 0.75
SCHEMBL127492 0.75
SCHEMBL679626 0.73 TSHR (0.56) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL5885289 0.73 ALDH1A1 (0.56) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL679947 0.73 HRH3 (0.47) ALDH1A1TSHR
SCHEMBL2220712 0.73 TRPA1 (0.56) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL9609757 0.73 TSHR (0.56) TRPA1ALDH1A1TSHRCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022046163-A1 CATIONIC POLYMERS COMPRISING NITROGEN-CONTAINING HETEROCYCLES AND THEIR APPLICATION IN WELLBORE STABILITY SAUDI ARABIAN OIL COMPANY (SA) 2022-03-03 WO disclosed
WO-2017037639-A1 A PROCESS FOR THE PREPARATION OF XYLENE LINKED CYCLAM COMPOUNDS FRESENIUS KABI ONCOLOGY LTD. (IN) 2017-03-09 WO disclosed