SCHEMBL679947

SCHEMBL679947

ICc1ccc(-c2ccc(CI)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 8/20 0.47
TAAR1 Q96RJ0 2/20 0.39
IDO1 P14902 2/20 0.35
AGXT P21549 2/20 0.35
ABCC4 O15439 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 1/20 0.35
PTGS1 P23219 1/20 0.35
HTT P42858 1/20 0.35
HRH4 Q9H3N8 1/20 0.35
MAOB P27338 2/20 0.33
CYP3A4 P08684 2/20 0.32
FFAR1 O14842 1/20 0.32
CYP17A1 P05093 1/20 0.32
CYP19A1 P11511 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL649682 0.89 ALDH1A1 (0.37) HRH3IDO1TSHRCYP3A4ALDH1A1
SCHEMBL4623627 0.88 TAAR1 (0.56) TAAR1IDO1AGXTABCC4LMNA
SCHEMBL15161136 0.86 TP53 (0.43) HRH3TAAR1TSHRALDH1A1TP53
SCHEMBL17109523 0.86 IDO1 (0.46) HRH3TAAR1IDO1AGXTALDH1A1
SCHEMBL15037627 0.86 ESR1 (0.58) TAAR1IDO1LMNACYP3A4ALDH1A1
SCHEMBL17432938 0.86 MAOB (0.52) TAAR1IDO1AGXTLMNAMAOB
SCHEMBL15037702 0.84 MAPT (0.55) LMNACYP3A4CYP17A1CYP19A1CYP11B1
SCHEMBL24093424 0.80 MAOB (0.59) TAAR1IDO1AGXTTSHRMAOB
SCHEMBL23512614 0.80 CA2 (0.54) TSHR
SCHEMBL24438521 0.80 ERN1 (0.41) HRH3IDO1AGXTMAOBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023063122-A1 CURABLE RESIN COMPOSITION, PREPREG, AND CURED PRODUCT OF SAME 日本化薬株式会社 2023-04-20 WO disclosed
CN-108884302-B Thermosetting resin composition, prepreg, and cured product thereof 日本化药株式会社 2023-03-28 CN disclosed
US-20170369636-A1 Aromatic Amine Resin, Epoxy Resin Composition And Cured Product Thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-12-28 US disclosed
EP-3248996-A1 AROMATIC AMINE RESIN, AND EPOXY RESIN COMPOSITION AND CURED PRODUCT THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2017-11-29 EP disclosed
CN-104136480-B Resin composition for encapsulation and electronic device using the same 住友电木株式会社 2017-05-31 CN disclosed
CN-104114639-B Resin composition for sealing and the electronic installation using it 住友电木株式会社 2016-11-09 CN disclosed
US-9136194-B2 Resin composition for encapsulation and electronic device using the same SUMITOMO BAKELITE CO., LTD. (JP) 2015-09-15 US disclosed
US-20150152258-A1 RESIN COMPOSITION FOR ENCAPSULATION AND ELECTRONIC DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2015-06-04 US disclosed
US-20150152230-A1 THERMOSETTING RESIN COMPOSITION AND ELECTRICAL DEVICE USING SAME HITACHI, LTD. (JP) 2015-06-04 US disclosed
US-20150054180-A1 RESIN COMPOSITION FOR ENCAPSULATION AND ELECTRONIC DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2015-02-26 US disclosed
EP-1243599-A1 PROCESS FOR PRODUCING VINYL POLYMER HAVING FUNCTIONAL GROUP AT END AND VINYL POLYMER HAVING FUNCTIONAL GROUP AT END SEKISUI CHEMICAL CO., LTD. (JP) 2002-09-25 EP disclosed
US-6417178-B1 Amyloid binding nitrogen-linked compounds for the antemortem diagnosis of alzheimer's disease, in vivo imaging and prevention of amyloid deposits UNIVERSITY OF PITTSBURGH 2002-07-09 US disclosed
US-6168776-B1 Alkyl, alkenyl and alkynyl Chrysamine G derivatives for the antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition UNIVERSITY OF PITTSBURGH 2001-01-02 US disclosed
US-6133259-A DIAGNOSIS OF ALZHEIMER'S DISEASE UNIVERSITY OF PITTSBURGH (US) 2000-10-17 US disclosed
US-6114175-A AMYLOID-BINDING COMPOUNDS WHICH ARE NON-AZO DERIVATIVES OF CHRYSAMINE G TO DETERMINE DEGREE OF BRAIN DEPOSITS QUANTITATIVELY CHARACTERIZED BY AMYLOIDOSIS; DOWN'S SYNDROME; PREVENT CELL DEGENERATION; RADIOACTIVE IMAGING UNIVERSITY OF PITTSBURGH (US) 2000-09-05 US disclosed
EP-0311387-B1 AROMATIC AMINE RESINS, THEIR PRODUCTION PROCESS AND THERMOSETTING RESIN COMPOSITIONS MAKING USE OF THE SAME MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-11 EP disclosed
US-5145949-A Production process for making aromatic amine resins MITSUI TOATSU CHEMICALS, INC. (JP) 1992-09-08 US disclosed
US-5106953-A Reacting aromatic amines with bishalogenomethyl derivatives; curing agents or raw materials for polyamides MITSUI TOATSU CHEMICALS, INC. (JP) 1992-04-21 US disclosed
US-5051494-A A bismaleimide and an amino resin MITSUI TOATSU CHEMICALS, INC. (JP) 1991-09-24 US disclosed
US-4937318-A Aromatic amine resins MITSUI TOATSU CHEMICALS, INC. (JP) 1990-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170369636-A1 Aromatic Amine Resin, Epoxy Resin Composition And Cured Product Thereof H1-5, ASH2L, ASH1L HRH3 16/4885TAAR1 42/4885IDO1 2314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.