Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609585 | 0.91 | ALDH1A1 (0.49) | NAMPTSMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL18609409 | 0.86 | MRGPRX4 (0.56) | SMN1; SMN2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL18609408 | 0.85 | L3MBTL1 (0.52) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1NTRK1 | |
| SCHEMBL18609412 | 0.85 | MRGPRX4 (0.52) | SMN1; SMN2ALDH1A1L3MBTL1NTRK1 | |
| SCHEMBL18609825 | 0.85 | RXRA (0.53) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1NTRK1 | |
| SCHEMBL18609677 | 0.85 | ANO1 (0.46) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1NTRK1 | |
| SCHEMBL18609826 | 0.84 | HDAC1 (0.56) | SMN1; SMN2KDM4EALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL18609595 | 0.83 | L3MBTL1 (0.49) | SMN1; SMN2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL18610091 | 0.83 | KMT2A (0.45) | SMN1; SMN2ALDH1A1TSHRKMT2AHSD17B10 | |
| SCHEMBL18609828 | 0.83 | L3MBTL1 (0.48) | SMN1; SMN2ALDH1A1TSHRKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345892-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017038871-A1 | UREA DERIVATIVE AND USE THEREFOR | 東レ株式会社 | 2017-03-09 | — | — | WO | disclosed |