Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609412 | 0.94 | MRGPRX4 (0.52) | MRGPRX4L3MBTL1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL18609408 | 0.91 | L3MBTL1 (0.52) | MRGPRX4L3MBTL1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL18609825 | 0.87 | RXRA (0.53) | L3MBTL1SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL18609826 | 0.86 | HDAC1 (0.56) | L3MBTL1SMN1; SMN2ALDH1A1TDP1RAB9A | |
| SCHEMBL18609585 | 0.86 | ALDH1A1 (0.49) | L3MBTL1SMN1; SMN2ALDH1A1TDP1KMT2A | |
| SCHEMBL18609595 | 0.86 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2ALDH1A1TDP1RAB9A | |
| SCHEMBL18609587 | 0.86 | NAMPT (0.49) | L3MBTL1SMN1; SMN2ALDH1A1KMT2ATSHR | |
| SCHEMBL18609828 | 0.85 | L3MBTL1 (0.48) | L3MBTL1SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL18609417 | 0.84 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL18609677 | 0.84 | ANO1 (0.46) | L3MBTL1SMN1; SMN2ALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190010117-A1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES, INC. (JP) | 2019-01-10 | — | — | US | disclosed |
| EP-3345892-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |
| EP-3345892-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017038871-A1 | UREA DERIVATIVE AND USE THEREFOR | 東レ株式会社 | 2017-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190010117-A1 | UREA DERIVATIVE AND USE THEREFOR | UTS2R, SLC14A1, TMEM164 | MRGPRX4 2181/4885L3MBTL1 3000/4885SMN1; SMN2 3884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.