Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609408 | 0.92 | L3MBTL1 (0.52) | L3MBTL1HDAC1HDAC6HDAC11PLA2G1B | |
| SCHEMBL18609596 | 0.92 | L3MBTL1 (0.47) | L3MBTL1HDAC1HDAC6HDAC11PLA2G1B | |
| SCHEMBL18609825 | 0.92 | RXRA (0.53) | L3MBTL1HDAC1HDAC6HDAC11PLA2G1B | |
| SCHEMBL18609826 | 0.91 | HDAC1 (0.56) | L3MBTL1HDAC1HDAC6HDAC11PLA2G1B | |
| SCHEMBL20357398 | 0.90 | L3MBTL1 (0.43) | L3MBTL1HDAC1HDAC6HDAC11PLA2G1B | |
| SCHEMBL18609828 | 0.89 | L3MBTL1 (0.48) | L3MBTL1HDAC1HDAC6HDAC11PLA2G1B | |
| SCHEMBL18609814 | 0.89 | ALOX5 (0.49) | L3MBTL1HDAC1HDAC6HDAC11PLA2G1B | |
| SCHEMBL18609598 | 0.88 | MCHR1 (0.51) | L3MBTL1HDAC1HDAC6HDAC11PPARG | |
| SCHEMBL18609585 | 0.87 | ALDH1A1 (0.49) | L3MBTL1PLA2G1BATG4BKMT2ASMN1; SMN2 | |
| SCHEMBL20608399 | 0.87 | MTNR1B (0.44) | L3MBTL1HDAC1HDAC6HDAC11PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190010117-A1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES, INC. (JP) | 2019-01-10 | — | — | US | disclosed |
| EP-3345892-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |
| EP-3345892-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017038871-A1 | UREA DERIVATIVE AND USE THEREFOR | 東レ株式会社 | 2017-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190010117-A1 | UREA DERIVATIVE AND USE THEREFOR | UTS2R, SLC14A1, TMEM164 | L3MBTL1 3000/4885HDAC1 1681/4885HDAC6 2385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.