Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 3/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24137114 | 0.81 | ALDH1A1 (0.61) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL18291815 | 0.80 | ALDH1A1 (0.56) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17141748 | 0.78 | MEN1 (0.43) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14048578 | 0.78 | PTGS1 (0.44) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28987801 | 0.77 | CES2 (0.42) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14533723 | 0.77 | JAK2 (0.47) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL19139880 | 0.77 | CES2 (0.42) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28415313 | 0.77 | CES2 (0.42) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL18075688 | 0.77 | NPSR1 (0.41) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL20414941 | 0.77 | PDE2A (0.37) | CES2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524600-B1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS | SANOFI SA (FR) | 2021-11-17 | — | — | EP | disclosed |
| WO-2020243423-A1 | TEAD INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2020-12-03 | — | — | WO | disclosed |
| US-9661854-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2017-05-30 | — | — | US | disclosed |
| US-20170064962-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170064962-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | CES2 1624/4885KDM4E 1609/4885ALDH1A1 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.