SCHEMBL18612909

SCHEMBL18612909

N#CC(c1ccccc1)(c1ccccc1)C(C#N)(c1ccccc1)c1ccc(-c2ccc(C(c3ccccc3)C(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.36
CHRNA4 P43681 1/20 0.36
KIF11 P52732 3/20 0.35
TRPA1 O75762 1/20 0.34
TSHR P16473 1/20 0.34
PBRM1 Q86U86 1/20 0.34
ACP3 P15309 3/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
PGR P06401 1/20 0.32
ATM Q13315 1/20 0.32
CYP2C9 P11712 1/20 0.32
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31
OPRM1 P35372 1/20 0.31
DRD3 P35462 1/20 0.31
HPGDS O60760 1/20 0.31
PTGS2 P35354 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL296760 0.78 ATM (0.43) TRPA1TSHRCYP3A4CYP2D6ATM
SCHEMBL9243283 0.67 KIF11 (0.42) KIF11TSHRCYP3A4CYP2D6ATM
SCHEMBL11675721 0.66 KIF11 (0.50) KIF11CYP3A4CYP2C9
SCHEMBL448348 0.66 DPP4 (0.53) TSHRCYP2D6
SCHEMBL28827192 0.65 CYP2D6 (0.40) CYP3A4CYP2D6ATMDRD2DRD4
SCHEMBL9242359 0.64 ALDH1A1 (0.52) ATMCA12CA1CA2CA9
SCHEMBL1059122 0.63 CYP2D6 (0.49) TRPA1TSHRCYP3A4CYP2D6ATM
SCHEMBL1059119 0.63 CYP2D6 (0.49) TRPA1TSHRCYP3A4CYP2D6ATM
SCHEMBL29261466 0.63 CHRNB2 (0.42) CHRNB2CHRNA4KIF11TRPA1TSHR
SCHEMBL5356083 0.63 ATM (0.33) TSHRCYP3A4CYP2D6ATMDRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3344679-B1 METHOD FOR FRONTAL POLYMERIZATION OF CATIONICALLY POLYMERIZABLE MONOMERS UNIV WIEN TECH (AT) 2019-10-09 EP disclosed
WO-2017035551-A1 METHOD FOR FRONTAL POLYMERIZATION OF CATIONICALLY POLYMERIZABLE MONOMERS TECHNISCHE UNIVERSITÄT WIEN (AT) 2017-03-09 WO disclosed