Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296760 | 0.86 | ATM (0.43) | ALDH1A1TSHRRAB9AATMCYP2D6 | |
| SCHEMBL11153380 | 0.84 | KIF11 (0.43) | KIF11NOTUMALDH1A1TSHRSLC6A2 | |
| SCHEMBL9052398 | 0.77 | NOTUM (0.48) | KIF11NOTUMALDH1A1TSHRSLC6A2 | |
| SCHEMBL4339462 | 0.74 | NOTUM (0.50) | KIF11NOTUMALDH1A1TSHRSLC6A2 | |
| SCHEMBL11626646 | 0.72 | DRD2 (0.50) | KIF11RAB9AATMCYP2D6DRD2 | |
| SCHEMBL5309862 | 0.72 | CYP19A1 (0.50) | KIF11NOTUMALDH1A1TSHRSLC6A2 | |
| SCHEMBL28827192 | 0.71 | CYP2D6 (0.40) | ALDH1A1RAB9AATMCYP2D6DRD2 | |
| SCHEMBL9203753 | 0.70 | KCNN4 (0.70) | KIF11NOTUMALDH1A1TSHRSLC6A2 | |
| SCHEMBL9203743 | 0.70 | NOTUM (0.46) | KIF11NOTUMALDH1A1TSHRSLC6A2 | |
| SCHEMBL26294659 | 0.70 | ALDH1A1 (0.55) | KIF11NOTUMALDH1A1TSHRSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672652-A1 | Stabilizers for the prevention of polymerization of (meth)acrylic acid and esters thereof | CIBA-GEIGY AG (CH) | 1995-09-20 | — | — | EP | disclosed |