Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18613655 | 0.92 | KMT2A (0.61) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL28151715 | 0.88 | KMT2A (0.51) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL27367054 | 0.84 | KMT2A (0.52) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL8387984 | 0.81 | BCL9 (0.58) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL28770121 | 0.81 | KMT2A (0.57) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL2058361 | 0.80 | ALDH1A1 (0.55) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL8207857 | 0.79 | KMT2A (0.55) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL19690545 | 0.79 | KMT2A (0.55) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL19690708 | 0.79 | HTT (0.66) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL11579236 | 0.79 | KMT2A (0.60) | KMT2ALMNAALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240050573-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2024-02-15 | — | — | US | disclosed |
| US-11738087-B2 | Lymph directing prodrugs | MONASH UNIVERSITY (AU) | 2023-08-29 | — | — | US | disclosed |
| US-20180243425-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2018-08-30 | — | — | US | disclosed |
| EP-3347340-A1 | LYMPH DIRECTING PRODRUGS | Monash University (AU) | 2018-07-18 | — | — | EP | disclosed |
| WO-2017041139-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2017-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240050573-A1 | LYMPH DIRECTING PRODRUGS | LTA, ABCB11, LYN | KMT2A 4086/4885LMNA 3766/4885ALDH1A1 1056/4885 |
| US-20180243425-A1 | LYMPH DIRECTING PRODRUGS | MLNR, ABCB11, MLN | KMT2A 3956/4885LMNA 3302/4885ALDH1A1 1385/4885 |
| US-11738087-B2 | Lymph directing prodrugs | MLNR, ABCB11, MLN | KMT2A 3956/4885LMNA 3302/4885ALDH1A1 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.