Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18613656 | 0.92 | KMT2A (0.53) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL8387984 | 0.88 | BCL9 (0.58) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL11456829 | 0.85 | KMT2A (0.50) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL23799441 | 0.84 | KMT2A (0.51) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL28151715 | 0.84 | KMT2A (0.51) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL15412367 | 0.84 | KMT2A (0.44) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL21994120 | 0.84 | THRB (0.45) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL22425697 | 0.83 | PPARG (0.44) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL16281795 | 0.83 | PPARG (0.44) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL170186 | 0.83 | KMT2A (0.61) | KMT2AALDH1A1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063537-A | Prodrugs of directed lymphatics | 莫纳什大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-108137482-B | Prodrugs of directed lymphatics | 莫纳什大学 | 2024-03-15 | — | — | CN | disclosed |
| US-20240050573-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2024-02-15 | — | — | US | disclosed |
| US-11738087-B2 | Lymph directing prodrugs | MONASH UNIVERSITY (AU) | 2023-08-29 | — | — | US | disclosed |
| CN-114031658-A | Lymphatic prodrugs | 莫纳什大学 | 2022-02-11 | — | — | CN | disclosed |
| US-20180243425-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2018-08-30 | — | — | US | disclosed |
| EP-3347340-A1 | LYMPH DIRECTING PRODRUGS | Monash University (AU) | 2018-07-18 | — | — | EP | disclosed |
| CN-108137482-A | Lymphatic prodrugs | 莫纳什大学 | 2018-06-08 | — | — | CN | disclosed |
| WO-2017041139-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2017-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240050573-A1 | LYMPH DIRECTING PRODRUGS | LTA, ABCB11, LYN | KMT2A 4086/4885ALDH1A1 1056/4885LMNA 3766/4885 |
| US-20180243425-A1 | LYMPH DIRECTING PRODRUGS | MLNR, ABCB11, MLN | KMT2A 3956/4885ALDH1A1 1385/4885LMNA 3302/4885 |
| US-11738087-B2 | Lymph directing prodrugs | MLNR, ABCB11, MLN | KMT2A 3956/4885ALDH1A1 1385/4885LMNA 3302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.