Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18617396 | 0.81 | — | — | |
| SCHEMBL18616572 | 0.78 | KMT2A (0.41) | MPOMEN1KMT2ANR4A2 | |
| SCHEMBL18617663 | 0.78 | SMN1; SMN2 (0.33) | MPOMEN1KMT2ANR4A2 | |
| SCHEMBL18616509 | 0.70 | MPO (0.39) | MPONPC1RAB9A | |
| SCHEMBL18617434 | 0.69 | MPO (0.40) | MPONPC1RAB9A | |
| SCHEMBL18617442 | 0.65 | TNF (0.37) | MPOMEN1KMT2ANR4A2MAPT | |
| SCHEMBL18616504 | 0.62 | MPO (0.33) | MPOMEN1KMT2A | |
| SCHEMBL17595014 | 0.61 | ALDH1A1 (0.43) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL18620550 | 0.60 | NOS2 (0.42) | MAPT | |
| SCHEMBL3793479 | 0.60 | GAA (0.43) | KMT2ANR4A2NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040449-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |