Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14856784 | 0.90 | FAAH (0.36) | FAAHBDKRB1TRPV1 | |
| SCHEMBL2811317 | 0.89 | BDKRB1 (0.43) | BDKRB1FPR2EGFRCNR1 | |
| SCHEMBL185951 | 0.85 | TRPV1 (0.33) | FAAHBDKRB1TRPV1FPR2 | |
| SCHEMBL14856806 | 0.80 | TRPV1 (0.36) | FAAHBDKRB1TRPV1FPR2POLB | |
| SCHEMBL13128619 | 0.79 | BDKRB1 (0.43) | BDKRB1CNR1 | |
| SCHEMBL186372 | 0.79 | RAB9A (0.40) | FAAHBDKRB1TRPV1FPR2 | |
| SCHEMBL196872 | 0.78 | BDKRB1 (0.40) | FAAHBDKRB1TRPV1 | |
| SCHEMBL2805107 | 0.78 | BDKRB1 (0.42) | BDKRB1CNR1 | |
| SCHEMBL185605 | 0.78 | FAAH (0.46) | FAAHBDKRB1TRPV1POLB | |
| SCHEMBL14856605 | 0.77 | FAAH (0.35) | FAAHBDKRB1TRPV1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097372-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |