Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815680 | 0.89 | ACMSD (0.54) | FFAR1PTPN5TDP1ACMSDBACE1 | |
| SCHEMBL15725304 | 0.88 | CA2 (0.52) | TDP1BACE1TAAR1CA2KCNH2 | |
| SCHEMBL19738377 | 0.84 | ESR1 (0.61) | FFAR1MEN1ESR1KMT2AKCNH2 | |
| SCHEMBL17547068 | 0.83 | ESR1 (0.65) | TDP1ACMSDMAOBBACE1CA2 | |
| SCHEMBL20413 | 0.82 | CA2 (0.59) | FFAR1TDP1BACE1TAAR1CA2 | |
| SCHEMBL25956648 | 0.80 | HSD11B1 (0.53) | FFAR1MEN1KMT2A | |
| SCHEMBL15725310 | 0.80 | BACE1 (0.45) | FFAR1BACE1TAAR1CA2 | |
| SCHEMBL29892442 | 0.79 | MEN1 (0.55) | PTPN5TDP1DHODHCA2MEN1 | |
| SCHEMBL19738378 | 0.79 | FFAR1 (0.41) | FFAR1PTPN5DHODHMAOBBACE1 | |
| SCHEMBL19730229 | 0.79 | MEN1 (0.46) | FFAR1MAOBTAAR1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9594283-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-03-14 | — | — | US | disclosed |