SCHEMBL18629883

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7369949	0.83	CA5A (0.43)	CA5AKDM4ESMN1; SMN2LMNACYP2C9
	SCHEMBL31520153	0.81	KDM4E (0.50)	KDM4ELMNACYP2C9L3MBTL1ALDH1A1
	SCHEMBL32669678	0.81	KDM4E (0.50)	KDM4ELMNACYP2C9L3MBTL1ALDH1A1
	SCHEMBL23317588	0.80	CYP11B1 (0.41)	CA5AKDM4ESMN1; SMN2CYP2C9L3MBTL1
	SCHEMBL22230775	0.80	TTR (0.42)	CA5AKDM4ESMN1; SMN2LMNACYP2C9
	SCHEMBL18629884	0.80	GSK3B (0.45)	CYP2C9ALDH1A1MEN1KMT2A
	SCHEMBL1644952	0.80	CA5A (0.56)	CA5ASMN1; SMN2LMNACYP2C9ALDH1A1
	SCHEMBL7662707	0.76	VNN1 (0.45)	KDM4ESMN1; SMN2CYP11B1CYP11B2ALDH1A1
	SCHEMBL2369495	0.76	S1PR3 (0.51)	CYP11B1CYP11B2ALDH1A1S1PR3MEN1
	SCHEMBL30737737	0.76	S1PR3 (0.51)	CYP11B1CYP11B2ALDH1A1S1PR3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.