Sugi Predict

Sugi Predict / Compounds / SCHEMBL1644952

SCHEMBL1644952

SCHEMBL1644952

CC(=O)c1cc(C)c(O)c(C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA5A P35218 1/20 0.56
▸ LMNA P02545 1/20 0.52
▸ CA1 P00915 1/20 0.50
▸ CA2 P00918 1/20 0.50
▸ ESR1 P03372 3/20 0.46
▸ CYP1A2 P05177 1/20 0.45
▸ CYP3A4 P08684 1/20 0.45
▸ CYP2D6 P10635 1/20 0.45
▸ CYP2C9 P11712 1/20 0.45
▸ CYP2B6 P20813 1/20 0.45
▸ KMT2A Q03164 4/20 0.43
▸ MEN1 O00255 3/20 0.43
▸ NPC1 O15118 2/20 0.43
▸ HSD17B1 P14061 1/20 0.42
▸ MAPT P10636 2/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ ALOX5 P09917 1/20 0.41
▸ PTGS1 P23219 1/20 0.41
▸ PTGS2 P35354 1/20 0.41
▸ MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13144722 0.88 CA5A (0.50) CA5ALMNACA1CA2ESR1
SCHEMBL18629882 0.86 CA5A (0.48) CA5ALMNACA1CA2ESR1
SCHEMBL6900728 0.86 CA5A (0.48) CA5ALMNACA1CA2ESR1
SCHEMBL9863598 0.84 TTR (0.48) CA5ALMNACA1CA2ESR1
SCHEMBL2716447 0.84 TTR (0.48) CA5ALMNACA1CA2ESR1
SCHEMBL454210 0.83 HMGB1 (0.56) CA5ALMNACYP3A4CYP2C9KMT2A
SCHEMBL96185 0.81 CA5A (0.52) CA5ALMNACYP3A4KMT2ANPC1
SCHEMBL1448473 0.81 CA1 (0.52) LMNACA1CA2ESR1CYP1A2
SCHEMBL2754944 0.81 CA5A (0.43) CA5ALMNACA1CA2ESR1
SCHEMBL9911749 0.81 CYP1A2 (0.57) CA5ALMNACA1CA2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066269-B1 TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS JANSSEN PHARMACEUTICA NV (BE) 2005-05-11 — — EP claimed
US-20020115668-A1 Trisubstituted 1,3,5-triazine derivatives DAEYAERT FREDERIK FRANS DESIRE (BE) 2002-08-22 — — US claimed
EP-1066269-A1 TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS JANSSEN PHARMACEUTICA N.V. (BE) 2001-01-10 — — EP claimed
US-6150360-A ADMINISTERING TO A PATIENT SUFFERING FROM HUMAN IMMUNODEFICIENCY VIRUS INFECTION A TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVE JANSSEN PHARMACEUTICA N.V. (BE) 2000-11-21 — — US claimed
WO-1999050256-A1 TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS JANSSEN PHARMACEUTICA N.V. (BE) 1999-10-07 — — WO claimed
US-20250145587-A1 BROMODOMAIN INHIBITORS ABBVIE INC (US) 2025-05-08 — — US disclosed
CN-116102426-B Wide-absorption polymerizable ketene photoinitiator and preparation method and application thereof 合肥工业大学 2025-04-29 — — CN disclosed
WO-2025049767-A1 AMIDE PRODRUGS AND USES THEREOF AUTOBAHN THERAPEUTICS, INC. (US) 2025-03-06 — — WO disclosed
US-20240360124-A1 Bromodomain Inhibitors ABBVIE INC. (US) 2024-10-31 — — US disclosed
US-20230295513-A1 LIQUID CRYSTAL POLYESTER AND FILM COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-09-21 — — US disclosed
CN-116670106-A Crystalline 1, 1-tris (4-hydroxy-3, 5-dimethylphenyl) ethane and process for producing the same 本州化学工业株式会社 2023-08-29 — — CN disclosed
US-20230220179-A1 Processes for Producing Cyclic Olefins from Polymers and Re-Polymerization Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2023-07-13 — — US disclosed
US-4965400-A Preparation of 3,5-disubstituted-4-acetoxystyrene CLARIANT AG (CH) 1990-10-23 — — US disclosed
US-4927956-A 3,5-disubstituted-4-acetoxystyrene and process for its production HOECHST CELANESE CORPORATION (US) 1990-05-22 — — US disclosed
US-4927956-A 3,5-disubstituted-4-acetoxystyrene and process for its production HOECHST CELANESE CORPORATION (US) 1990-05-22 — — US disclosed
EP-0365340-A2 Copolymers of 4-hydroxystyrene and alkyl substituted-4-hydroxystyrene HOECHST CELANESE CORPORATION (US) 1990-04-25 — — EP disclosed
EP-0356070-A1 Synthesis of 4-acetoxystyrene oxide and related compounds HOECHST CELANESE CORPORATION (US) 1990-02-28 — — EP disclosed
EP-0338208-A1 Functionalized polyphenylene ether and method for its preparation HÜLS AKTIENGESELLSCHAFT (DE) 1989-10-25 — — EP disclosed
EP-0307752-A2 Poly(3-mono- and 3,5-disubstituted-4-acetoxystyrenes and 4-hydroxy-styrenes)and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-22 — — EP disclosed
EP-0307751-A2 3-mono- and 3,5-disubstituted-4-acetoxy and -4-hydroxystyrenes and process for their production HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115668-A1 Trisubstituted 1,3,5-triazine derivatives XDH, CCR5, CXCR1 CA5A 3357/4885LMNA 1515/4885CA1 4799/4885
US-20230220179-A1 Processes for Producing Cyclic Olefins from Polymers and Re-Polymerization Thereof COASY, PTGIS, PUF60 CA5A 2339/4885LMNA 4089/4885CA1 3169/4885
US-20250145587-A1 BROMODOMAIN INHIBITORS BRD4, BRD3, BRD1 CA5A 3828/4885LMNA 2472/4885CA1 3532/4885
US-20240360124-A1 Bromodomain Inhibitors BRD4, BRD3, BRD1 CA5A 4208/4885LMNA 2379/4885CA1 3394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.