Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18630143 | 0.94 | TGM2 (0.46) | TGM2GAAKMT2AMEN1MAPK1 | |
| SCHEMBL18636747 | 0.85 | GAA (0.43) | TGM2GAAL3MBTL1KMT2AMEN1 | |
| SCHEMBL11795978 | 0.84 | TGM2 (0.50) | TGM2GAAMAPK1ALDH1A1TSHR | |
| SCHEMBL21342737 | 0.79 | TRPV1 (0.45) | GAAL3MBTL1KMT2AMEN1MAPK1 | |
| SCHEMBL18630147 | 0.79 | TGM2 (0.49) | TGM2GAAKMT2AMEN1MAPK1 | |
| SCHEMBL11793243 | 0.78 | TGM2 (0.46) | TGM2GAAMAPK1ALDH1A1TSHR | |
| SCHEMBL22855686 | 0.78 | GAA (0.47) | TGM2GAAKMT2AMEN1MAPK1 | |
| SCHEMBL28511134 | 0.76 | TGM2 (0.49) | TGM2GAAKMT2AMAPK1ALDH1A1 | |
| SCHEMBL11796052 | 0.75 | GAA (0.45) | TGM2GAAZDHHC20ZDHHC2TRPV1 | |
| SCHEMBL27978331 | 0.73 | TGM2 (0.46) | TGM2GAAKMT2AMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3518863-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2023-11-15 | — | — | EP | disclosed |
| WO-2017042333-A1 | POLYMERIZABLE POLYACIDIC POLYMER | DENTSPLY DETREY GMBH (DE) | 2017-03-16 | — | — | WO | disclosed |