Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22855686 | 0.94 | GAA (0.47) | GAATHRATHRBTGM2ALDH1A1 | |
| SCHEMBL18630146 | 0.85 | TGM2 (0.42) | GAATGM2ALDH1A1L3MBTL1TSHR | |
| SCHEMBL18630160 | 0.81 | THRA (0.46) | GAATHRATHRBTGM2ALDH1A1 | |
| SCHEMBL18630143 | 0.78 | TGM2 (0.46) | GAATHRATHRBTGM2ALDH1A1 | |
| SCHEMBL11795978 | 0.75 | TGM2 (0.50) | GAATHRATHRBTGM2ALDH1A1 | |
| SCHEMBL21342736 | 0.74 | ALDH1A1 (0.45) | GAAALDH1A1CYP3A4EGFRMAPK1 | |
| SCHEMBL28511134 | 0.72 | TGM2 (0.49) | GAATGM2ALDH1A1BTKEGFR | |
| SCHEMBL11793243 | 0.71 | TGM2 (0.46) | GAATHRATHRBTGM2ALDH1A1 | |
| SCHEMBL4325063 | 0.70 | GAA (0.70) | GAATGM2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL27978331 | 0.70 | TGM2 (0.46) | GAATGM2ALDH1A1BTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141567-A1 | POLYMERIZABLE POLYACIDIC POLYMER | DENTSPLY DETREY GmbH (DE) | 2017-03-15 | — | — | EP | disclosed |