Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ATG7 | O95352 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18630409 | 0.86 | SLC29A1 (0.49) | SLC29A1 | |
| SCHEMBL18631613 | 0.84 | ATG7 (0.44) | SLC29A1ADORA2AATG7 | |
| SCHEMBL18630436 | 0.80 | UBA6 (0.40) | SLC29A1ATG7 | |
| SCHEMBL1795883 | 0.78 | ATG7 (0.57) | SLC29A1ATG7 | |
| SCHEMBL11889887 | 0.78 | ATG7 (0.57) | SLC29A1ATG7 | |
| SCHEMBL18630609 | 0.78 | HSP90B1 (0.36) | ADORA2AATG7ADORA2B | |
| SCHEMBL18630476 | 0.78 | DNPH1 (0.49) | — | |
| SCHEMBL18631625 | 0.77 | NNMT (0.40) | SLC29A1NNMT | |
| SCHEMBL18630477 | 0.76 | CYP1A2 (0.40) | ATG7NNMT | |
| SCHEMBL18630483 | 0.76 | ADK (0.37) | SLC29A1ATG7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170073367-A9 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES | MILLENIUM PHARMACEUTICALS, INC. | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073367-A9 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES | TYMP, TYMS, PPA1 | SLC29A1 1761/4885ADORA2A 1750/4885ATG7 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.