Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19426682 | 0.83 | ALDH1A1 (0.52) | KMT2ACA2HSD11B1CA9CA1 | |
| SCHEMBL27742205 | 0.81 | PSIP1 (0.48) | KMT2AHSD11B1TDP1POLB | |
| SCHEMBL1683277 | 0.71 | F2 (0.50) | PLCG1CA2F2PRSS1PRSS2 | |
| SCHEMBL3253487 | 0.71 | PLCG1 (1.00) | PLCG1KMT2ACA2HSD11B1F2 | |
| SCHEMBL9704914 | 0.69 | PLCG1 (0.70) | PLCG1KMT2ACA2HSD11B1F2 | |
| SCHEMBL5375 | 0.69 | PLCG1 (0.70) | PLCG1KMT2ACA2CA9CA1 | |
| SCHEMBL3109600 | 0.67 | PLCG1 (0.67) | PLCG1KMT2ACA2HSD11B1F2 | |
| SCHEMBL8488156 | 0.67 | PLCG1 (0.67) | PLCG1KMT2ACA2HSD11B1F2 | |
| SCHEMBL13825881 | 0.67 | PLCG1 (0.67) | PLCG1KMT2ACA2HSD11B1F2 | |
| SCHEMBL165340 | 0.67 | PLCG1 (0.67) | PLCG1KMT2ACA2HSD11B1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985645-B1 | Low molecular weight siloxanes with one functional group | GELEST INC (US) | 2017-03-15 | — | — | EP | disclosed |