Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19426682 | 0.82 | ALDH1A1 (0.52) | HSD11B1ALDH1A1MAPTNPC1LMNA | |
| SCHEMBL18634031 | 0.81 | PLCG1 (0.53) | HSD11B1POLBKMT2ATDP1 | |
| SCHEMBL13925011 | 0.78 | KEAP1 (0.59) | PSIP1HSD11B1POLBKEAP1NFE2L2 | |
| SCHEMBL12646350 | 0.76 | PSIP1 (0.58) | PSIP1HSD11B1POLBKEAP1NFE2L2 | |
| SCHEMBL17664702 | 0.76 | PSIP1 (0.34) | PSIP1POLBHTR6 | |
| SCHEMBL10292967 | 0.72 | PSIP1 (0.54) | PSIP1HSD11B1POLBKEAP1NFE2L2 | |
| SCHEMBL13655542 | 0.71 | ALDH1A1 (0.58) | KEAP1ALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL1952786 | 0.69 | PSIP1 (0.50) | PSIP1HSD11B1POLBKEAP1NFE2L2 | |
| SCHEMBL28021898 | 0.69 | PSIP1 (0.56) | PSIP1HSD11B1POLBKEAP1NFE2L2 | |
| SCHEMBL81874 | 0.68 | HTR6 (0.44) | PSIP1DUSP3PTPN5PTPN11HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101287729-A | GPCR agonists | PROSIDION LTD (GB) | 2008-10-15 | — | — | CN | disclosed |