Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KDM5C | P41229 | 2/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetoacetic Acid SCHEMBL23581266 | 0.89 | KDM4E (0.44) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| Acetoacetic Acid SCHEMBL30758649 | 0.89 | KDM4E (0.44) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| Acetoacetic Acid SCHEMBL1023325 | 0.86 | ALOX15 (0.56) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| Acetoacetic Acid SCHEMBL7747946 | 0.86 | ALOX15 (0.56) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| Acetoacetic Acid SCHEMBL7441846 | 0.86 | KDM4E (0.46) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| Acetoacetic Acid SCHEMBL447678 | 0.85 | — | — | |
| Acetoacetic Acid SCHEMBL10448884 | 0.85 | — | — | |
| Acetoacetic Acid SCHEMBL10941648 | 0.85 | LDHA (0.57) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| Acetoacetic Acid SCHEMBL21402364 | 0.85 | — | — | |
| Acetoacetic Acid SCHEMBL1406366 | 0.85 | LDHA (0.57) | KDM4EKDM5CEGLN1PHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8790632-B2 | Polymer-based tissue-adhesive form medical use | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2014-07-29 | — | — | US | disclosed |
| EP-1796745-B1 | POLYMER-BASED TISSUE-ADHESIVE FOR MEDICAL USE | DU PONT (US) | 2011-05-25 | — | — | EP | disclosed |
| EP-1749845-B1 | Composite materials and methods of making the same | ROHM & HAAS (US) | 2008-10-01 | — | — | EP | disclosed |
| EP-1796745-A2 | POLYMER-BASED TISSUE-ADHESIVE FOR MEDICAL USE | E.I.Du pont de nemours and company (US) | 2007-06-20 | — | — | EP | disclosed |
| US-20070032576-A1 | Composite materials and methods of making the same | LUNDQUIST ERIC G | 2007-02-08 | — | — | US | disclosed |
| EP-1749845-A1 | Composite materials and methods of making the same | Rohm and Haas Company (US) | 2007-02-07 | — | — | EP | disclosed |
| WO-2006042169-A2 | POLYMER-BASED TISSUE-ADHESIVE FOR MEDICAL USE | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-04-20 | — | — | WO | disclosed |
| US-20060079599-A1 | Polymer-based tissue-adhesive form medical use | ACTAMAX SURGICAL MATERIALS, LLC | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079599-A1 | Polymer-based tissue-adhesive form medical use | ADSL, SI, VCAM1 | KDM4E 1780/4885KDM5C 2721/4885EGLN1 664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.