Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | KRAS | P01116 | 8/20 | 0.52 |
| ▸ | HINT1 | P49773 | 1/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.50 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621842 | 0.87 | NT5E (0.54) | NT5ETGM2KRASHINT1IMPDH2 | |
| SCHEMBL4081026 | 0.86 | NT5E (0.60) | NT5ETGM2KRASHINT1IMPDH2 | |
| SCHEMBL5861503 | 0.86 | NT5E (0.60) | NT5ETGM2KRASHINT1IMPDH2 | |
| SCHEMBL30139102 | 0.85 | NT5E (0.58) | NT5ETGM2KRASHINT1IMPDH2 | |
| SCHEMBL1527362 | 0.85 | NT5E (0.59) | NT5ETGM2KRASHINT1IMPDH2 | |
| SCHEMBL407394 | 0.85 | NT5E (0.59) | NT5ETGM2KRASHINT1IMPDH2 | |
| SCHEMBL8436532 | 0.84 | TGM2 (0.54) | NT5ETGM2KRASHINT1IMPDH2 | |
| SCHEMBL17505123 | 0.84 | KRAS (0.65) | NT5ETGM2KRASHINT1IMPDH2 | |
| SCHEMBL19183426 | 0.83 | NT5E (0.57) | NT5ETGM2KRASHINT1IMPDH2 | |
| SCHEMBL8440067 | 0.83 | FUT5 (0.53) | NT5ETGM2KRASHINT1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12071620-B2 | Polynucleotides containing a morpholino linker | MODERNATX, INC. (US) | 2024-08-27 | — | — | US | disclosed |
| US-20230323344-A1 | POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER | ARES CAPITAL CORPORATION, AS AGENT | 2023-10-12 | — | — | US | disclosed |
| US-11434486-B2 | Polynucleotides containing a morpholino linker | MODERNATX, INC. (US) | 2022-09-06 | — | — | US | disclosed |
| US-20190078087-A1 | POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER | ARES CAPITAL CORPORATION, AS AGENT | 2019-03-14 | — | — | US | disclosed |
| WO-2017049286-A1 | POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER | MODERNA THERAPEUTICS, INC. (US) | 2017-03-23 | — | — | WO | disclosed |