Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892175 | 0.73 | SNCA (0.54) | ATMTAAR1MAPTLMNAHPGD | |
| SCHEMBL18643131 | 0.69 | NPC1 (0.47) | ALDH1A1CA1CA2MEN1KMT2A | |
| SCHEMBL18643353 | 0.69 | FAAH (0.49) | ALDH1A1MEN1KMT2AATMMAPT | |
| SCHEMBL18639760 | 0.66 | CCNA2 (0.35) | ALDH1A1MEN1KMT2AATMLMNA | |
| SCHEMBL18643176 | 0.65 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ALMNANPC1 | |
| SCHEMBL24517998 | 0.65 | CA1 (0.67) | ALDH1A1CA1CA2MEN1KMT2A | |
| SCHEMBL24517764 | 0.64 | MEN1 (0.53) | ALDH1A1CA1CA2MEN1KMT2A | |
| SCHEMBL27522271 | 0.64 | CA1 (1.00) | CA1CA2MEN1KMT2AL3MBTL1 | |
| SCHEMBL24517780 | 0.63 | CA1 (0.64) | ALDH1A1CA1CA2MEN1KMT2A | |
| SCHEMBL18642817 | 0.63 | POLB (0.58) | ALDH1A1MEN1KMT2AL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440550-B1 | INDOLE AMIDE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIV LEUVEN KATH (BE) | 2017-03-15 | — | — | EP | disclosed |