Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.53 |
| ▸ | FEN1 | P39748 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18645205 | 0.84 | HTR6 (0.55) | HTR6FEN1CYP2C9BCHEFNTA | |
| SCHEMBL30111813 | 0.83 | BTK (0.46) | HTR6BACE1CTSDHPGDSHCAR1 | |
| SCHEMBL23450731 | 0.83 | BTK (0.46) | HTR6BACE1CTSDHPGDSHCAR1 | |
| SCHEMBL18289974 | 0.83 | BTK (0.46) | HTR6BACE1CTSDHPGDSHCAR1 | |
| SCHEMBL18644666 | 0.79 | SRC (0.45) | BACE1CTSDHPGDSHCAR1CCNK | |
| SCHEMBL24030203 | 0.74 | FEN1 (0.49) | HTR6FEN1BACE1CTSDCYP2C9 | |
| SCHEMBL24030205 | 0.74 | FEN1 (0.49) | HTR6FEN1BACE1CTSDCYP2C9 | |
| SCHEMBL24030429 | 0.74 | FEN1 (0.49) | HTR6FEN1BACE1CTSDCYP2C9 | |
| SCHEMBL15145746 | 0.73 | TGFBR1 (0.50) | BACE1TGFBR1 | |
| SCHEMBL24590579 | 0.72 | KDM4E (0.37) | SCN9AHCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017041536-A1 | OXO-DIHYDROIMIDAZO PYRIDINE COMPOUND AND APPLICATIONS THEREOF | 东莞市真兴贝特医药技术有限公司 | 2017-03-16 | — | — | WO | disclosed |