Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23870191 | 0.79 | AOC3 (0.40) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL23870165 | 0.79 | NDUFS8 (0.41) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL24106084 | 0.71 | AOC3 (0.41) | MAPTSMN1; SMN2HPGDHTTLMNA | |
| SCHEMBL24110662 | 0.71 | PLK1 (0.65) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL21116106 | 0.70 | PLK1 (0.63) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL18697940 | 0.69 | TRPV1 (0.42) | POLBHTTPLK1 | |
| SCHEMBL19601257 | 0.69 | NPC1 (0.58) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL6740785 | 0.69 | ALDH1A1 (0.64) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL20031971 | 0.69 | HDAC3 (0.45) | NPC1RAB9APOLB | |
| SCHEMBL7291413 | 0.69 | SMN1; SMN2 (0.76) | NPC1MAPTRAB9APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180042843-A1 | HIGH DENSITY PEPTIDE POLYMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180042843-A1 | HIGH DENSITY PEPTIDE POLYMERS | ERMP1, PARL, PRAP1 | NPC1 1559/4885MAPT 2736/4885RAB9A 712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.