Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24961123 | 0.87 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1LMNARAB9ANPC1 | |
| SCHEMBL13077892 | 0.83 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1LMNARAB9ANPC1 | |
| SCHEMBL18971802 | 0.80 | RAB9A (0.56) | ALDH1A1L3MBTL1LMNARAB9ANPC1 | |
| SCHEMBL193533 | 0.74 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1LMNARAB9ANPC1 | |
| SCHEMBL569032 | 0.74 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1LMNARAB9ANPC1 | |
| SCHEMBL6319718 | 0.73 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1LMNARAB9ANPC1 | |
| SCHEMBL6647582 | 0.73 | RAB9A (0.67) | ALDH1A1L3MBTL1LMNARAB9ANPC1 | |
| SCHEMBL6275655 | 0.73 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1LMNARAB9ANPC1 | |
| SCHEMBL28727291 | 0.72 | SMN1; SMN2 (0.65) | ALDH1A1L3MBTL1LMNARAB9ANPC1 | |
| SCHEMBL2170056 | 0.72 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1LMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10370344-B2 | 2-oxothiazole compounds and method of using same for chronic inflammatory disorders | AVEXXIN AS (NO) | 2019-08-06 | — | — | US | disclosed |
| US-20170166539-A1 | COMPOUND | AVEXXIN AS (NO) | 2017-06-15 | — | — | US | disclosed |
| US-9597318-B2 | 2-oxothiazole compounds and method of using same for chronic inflammatory disorders | AVEXXIN AS (NO) | 2017-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166539-A1 | COMPOUND | CBR1, CBR3, CCR1 | ALDH1A1 1317/4885L3MBTL1 753/4885LMNA 2112/4885 |
| US-10370344-B2 | 2-oxothiazole compounds and method of using same for chronic inflammatory disorders | CX3CR1, LTC4S, CBR1 | ALDH1A1 1588/4885L3MBTL1 351/4885LMNA 3006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.