Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 5/20 | 0.55 |
| ▸ | ESRRB | O95718 | 2/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | KDM5A | P29375 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865785 | 0.92 | ADORA2A (0.59) | ADORA2ANAMPTPRSS1CTSGCTRB1 | |
| SCHEMBL24871621 | 0.89 | ESRRG (0.55) | ESRRGESRRBADORA2AGFERMPO | |
| SCHEMBL13483866 | 0.85 | RAB9A (0.60) | ESRRGESRRBRAB9AMAPTNPC1 | |
| SCHEMBL6024562 | 0.85 | NPC1 (0.58) | ADORA2ANAMPTRAB9AMAPTNPC1 | |
| SCHEMBL22040703 | 0.85 | HDAC1 (0.60) | ADORA2ANAMPTHDAC3HDAC1HDAC2 | |
| SCHEMBL10224288 | 0.82 | PRSS1 (0.67) | ESRRGADORA2ANAMPTPRSS1CTSG | |
| SCHEMBL5687748 | 0.81 | MLYCD (0.69) | ESRRGESRRBGFERMPOCYP3A4 | |
| SCHEMBL12388322 | 0.81 | PLK1 (0.59) | ADORA2ACYP3A4NAMPTSMN1; SMN2HDAC3 | |
| SCHEMBL23116863 | 0.81 | GFER (0.53) | ESRRGESRRBGFERMPOCYP3A4 | |
| SCHEMBL22618725 | 0.80 | RAB9A (0.56) | ADORA2AHIF1ANAMPTPRSS1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170081346-A1 | MESOSCOPIC MATERIALS COMPRISED OF ORDERED SUPERLATTICES OF MICROPOROUS METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081346-A1 | MESOSCOPIC MATERIALS COMPRISED OF ORDERED SUPERLATTICES OF MICROPOROUS METAL-ORGANIC FRAMEWORKS | MCM2, YTHDF2, MCM6 | ESRRG 4375/4885ESRRB 4857/4885ADORA2A 3228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.