Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | FADS1 | O60427 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5063446 | 1.00 | KEAP1 (0.56) | KEAP1ERAP1FADS1ALDH1A1KDM4E | |
| SCHEMBL31160842 | 0.85 | KEAP1 (0.49) | KEAP1FADS1ALDH1A1KDM4EHDAC1 | |
| SCHEMBL17774895 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4ECA2CA1KDM4C | |
| SCHEMBL31372600 | 0.81 | KEAP1 (0.44) | KEAP1FADS1ALDH1A1KDM4E | |
| SCHEMBL23440037 | 0.78 | ALDH1A1 (0.69) | FADS1ALDH1A1KDM4ECA2CA1 | |
| SCHEMBL1533823 | 0.78 | ALDH1A1 (0.69) | FADS1ALDH1A1KDM4ECA2CA1 | |
| SCHEMBL690577 | 0.77 | KEAP1 (0.61) | KEAP1FADS1ALDH1A1HDAC1GAA | |
| SCHEMBL15610319 | 0.76 | ALOX5 (0.48) | ERAP1ALDH1A1KDM4ECA2CA1 | |
| SCHEMBL15610318 | 0.76 | ALOX5 (0.48) | ERAP1ALDH1A1KDM4ECA2CA1 | |
| SCHEMBL15610560 | 0.76 | ALOX5 (0.48) | ERAP1ALDH1A1KDM4ECA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
| EP-1867639-A1 | UREA DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | AVPR2, UTS2R, GPR119 | KEAP1 2330/4885ERAP1 1228/4885FADS1 1522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.