Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21587657 | 0.75 | KDM4E (0.53) | ALDH1A1KDM4EMAPK1POLBMAPT | |
| SCHEMBL19431069 | 0.75 | APLNR (0.56) | ALDH1A1KDM4EPOLBMAPTTSHR | |
| SCHEMBL31263175 | 0.74 | KDM4E (0.52) | ALDH1A1KDM4EMAPK1POLBMAPT | |
| SCHEMBL9804694 | 0.74 | KDM4E (0.61) | ALDH1A1KDM4EMAPK1POLBMAPT | |
| SCHEMBL2596090 | 0.73 | KDM4E (0.54) | ALDH1A1KDM4EMAPK1POLBMAPT | |
| SCHEMBL21587706 | 0.73 | KDM4E (0.64) | ALDH1A1KDM4EMAPK1POLBMAPT | |
| SCHEMBL4780301 | 0.73 | ALDH1A1 (0.54) | ALDH1A1KDM4EPOLBTSHRAPLNR | |
| SCHEMBL31263231 | 0.72 | KDM4E (0.50) | ALDH1A1KDM4EMAPK1POLBMAPT | |
| SCHEMBL9831262 | 0.71 | KDM4E (0.64) | ALDH1A1KDM4EMAPK1POLBMAPT | |
| SCHEMBL28191688 | 0.70 | KDM4E (0.63) | ALDH1A1KDM4EMAPK1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021061823-A1 | CHEMICAL COMPOUNDS | Boragen, Inc. (US) | 2021-04-01 | — | — | WO | disclosed |
| WO-2021061823-A1 | CHEMICAL COMPOUNDS | Boragen, Inc. (US) | 2021-04-01 | — | — | WO | disclosed |
| US-10167283-B2 | β-lactamase inhibitors and uses thereof | SUANZHU PHARMA CO., LTD. (CN) | 2019-01-01 | — | — | US | disclosed |
| US-20180148448-A1 | ß-LACTAMASE INHIBITORS AND USES THEREOF | Xuanzhu Pharma Co., Ltd. (CN) | 2018-05-31 | — | — | US | disclosed |
| US-20180148448-A1 | ß-LACTAMASE INHIBITORS AND USES THEREOF | Xuanzhu Pharma Co., Ltd. (CN) | 2018-05-31 | — | — | US | disclosed |
| EP-3281942-A1 | B-LACTAMASE INHIBITOR AND APPLICATION THEREOF | Xuanzhu Pharma Co., Ltd. (CN) | 2018-02-14 | — | — | EP | disclosed |
| WO-2017167218-A1 | ANTIBACTERIAL COMPOSITION AND USE THEREOF | 山东轩竹医药科技有限公司 | 2017-10-05 | — | — | WO | disclosed |
| WO-2017045510-A1 | Β-LACTAMASE INHIBITOR AND APPLICATION THEREOF | 山东轩竹医药科技有限公司 | 2017-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167283-B2 | β-lactamase inhibitors and uses thereof | MGAM, LCT, ALPI | ALDH1A1 269/4885KDM4E 918/4885MAPK1 4340/4885 |
| US-20180148448-A1 | ß-LACTAMASE INHIBITORS AND USES THEREOF | MGAM, LCT, ALPI | ALDH1A1 257/4885KDM4E 930/4885MAPK1 4336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.