Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.36 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | ACP3 | P15309 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | RXRB | P28702 | 2/20 | 0.31 |
| ▸ | RXRG | P48443 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18586306 | 0.85 | MGLL (0.48) | MGLLIDO1TRPV6ORAI1ORAI2 | |
| SCHEMBL17677146 | 0.83 | MGLL (0.47) | MGLLIDO1TRPV6ORAI1ORAI2 | |
| SCHEMBL30002291 | 0.83 | MGLL (0.47) | MGLLIDO1TRPV6ORAI1ORAI2 | |
| SCHEMBL28378199 | 0.81 | ENPP2 (0.41) | MGLLENPP2 | |
| SCHEMBL126169 | 0.81 | MGLL (0.61) | MGLLIDO1TRPV6ORAI1ORAI2 | |
| SCHEMBL16164272 | 0.81 | MGLL (0.61) | MGLLIDO1TRPV6ORAI1ORAI2 | |
| SCHEMBL28896242 | 0.79 | MGLL (0.59) | MGLLIDO1TRPV6ORAI1ORAI2 | |
| SCHEMBL30036309 | 0.79 | MGLL (0.59) | MGLLIDO1TRPV6ORAI1ORAI2 | |
| SCHEMBL24229617 | 0.79 | MGLL (0.43) | MGLLIDO1 | |
| SCHEMBL5776968 | 0.79 | IDO1 (0.54) | IDO1CES2MTORRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170081273-A1 | Serotonin Receptor-Targeting Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081273-A1 | Serotonin Receptor-Targeting Compounds and Methods | HTR1A, HTR2C, HTR7 | MGLL 3917/4885IDO1 202/4885TRPV6 1078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.