Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.41 |
| ▸ | LPL | P06858 | 5/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18656335 | 0.81 | MGLL (0.48) | ENPP2MGLL | |
| SCHEMBL2002928 | 0.78 | — | — | |
| SCHEMBL2230985 | 0.77 | ENPP2 (0.67) | ENPP2LPLLIPGF11CA4 | |
| SCHEMBL3781044 | 0.76 | ENPP2 (0.60) | ENPP2LPLLIPGF11CA4 | |
| SCHEMBL1191308 | 0.74 | LPL (0.58) | ENPP2LPLLIPGF11CA4 | |
| SCHEMBL1690441 | 0.74 | ENPP2 (0.41) | ENPP2LPLLIPGF11CA4 | |
| SCHEMBL3791528 | 0.74 | LPL (0.58) | ENPP2LPLLIPGF11MGLL | |
| SCHEMBL7652222 | 0.70 | ENPP2 (0.35) | ENPP2LPLLIPGCA1CA2 | |
| SCHEMBL1651131 | 0.70 | — | — | |
| SCHEMBL16193057 | 0.70 | TAAR1 (0.32) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409647-B | Preparation method of apatinib | 盐城师范学院 | 2020-03-24 | — | — | CN | disclosed |