Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14948713 | 0.85 | ESRRB (0.43) | ALDH1A1L3MBTL1KMT2APOLBMAPT | |
| SCHEMBL15452092 | 0.81 | APAF1 (0.39) | ALDH1A1L3MBTL1POLBMAPT | |
| SCHEMBL23008679 | 0.81 | ALDH1A1 (0.53) | ALDH1A1ATMCTSSMAPK1L3MBTL1 | |
| SCHEMBL19273823 | 0.81 | APAF1 (0.39) | ALDH1A1L3MBTL1POLBMAPT | |
| SCHEMBL19273972 | 0.79 | NPC1 (0.33) | ALDH1A1ATMPOLBMAPTSMN1; SMN2 | |
| SCHEMBL19274004 | 0.79 | NPC1 (0.33) | ALDH1A1ATMPOLBMAPTSMN1; SMN2 | |
| SCHEMBL11057964 | 0.77 | ALDH1A1 (0.51) | ALDH1A1ATMCTSSMAPK1L3MBTL1 | |
| SCHEMBL18656643 | 0.76 | PIN1 (0.39) | ALDH1A1L3MBTL1KMT2ATDP1POLB | |
| SCHEMBL13743037 | 0.75 | SMN1; SMN2 (0.36) | ALDH1A1ATML3MBTL1KMT2ATDP1 | |
| SCHEMBL25207205 | 0.74 | ALDH1A1 (0.49) | ALDH1A1ATMCTSSMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9808531-B2 | Compounds and compositions for the treatment of ocular disorders | Graybug Vision, Inc. (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170080092-A1 | Compounds And Compositions for the Treatment of Ocular Disorders | Graybug Vision, Inc. (US) | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170080092-A1 | Compounds And Compositions for the Treatment of Ocular Disorders | PTGIR, PTGIS, CA2 | ALDH1A1 1010/4885ATM 3274/4885CTSS 1304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.