Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | CASP7 | P55210 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18944215 | 0.92 | NR1I2 (0.36) | NR1I2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL18663914 | 0.86 | NR1I2 (0.37) | NR1I2 | |
| SCHEMBL18944148 | 0.85 | NR1I2 (0.38) | NR1I2 | |
| SCHEMBL19955676 | 0.83 | NR1I2 (0.37) | NR1I2ALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL18546248 | 0.81 | NR1I2 (0.40) | NR1I2KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL18928972 | 0.80 | NR1I2 (0.33) | NR1I2 | |
| SCHEMBL18928302 | 0.80 | LMNA (0.40) | NR1I2KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL18928959 | 0.80 | NR1I2 (0.33) | NR1I2 | |
| SCHEMBL18929005 | 0.79 | NR1I2 (0.36) | NR1I2MAPTKMT2A | |
| SCHEMBL18928142 | 0.79 | HTR4 (0.33) | NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017046707-A1 | BENZOAZEPINE DERIVATIVES | VIIV HEALTHCARE UK LIMITED (GB) | 2017-03-23 | — | — | WO | disclosed |