Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18667549 | 0.88 | ATP4A (0.41) | — | |
| SCHEMBL18667607 | 0.87 | RAB9A (0.40) | RAB9ALMNAMAPTHDAC1HDAC2 | |
| SCHEMBL18667707 | 0.86 | RAB9A (0.39) | RAB9ALMNAMAPTHDAC1HDAC2 | |
| SCHEMBL21229029 | 0.84 | HDAC1 (0.42) | HDAC1HDAC2HDAC6XIAPPRKAB2 | |
| SCHEMBL26759172 | 0.82 | RAB9A (0.46) | RAB9ALMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL18667364 | 0.82 | L3MBTL1 (0.49) | LMNAHDAC1HDAC2HDAC6MAPK1 | |
| SCHEMBL18667570 | 0.82 | HRH3 (0.44) | — | |
| SCHEMBL18667605 | 0.82 | ATP4A (0.49) | KDM4E | |
| Hydrochloric Acid SCHEMBL18641385 | 0.81 | RAB9A (0.42) | RAB9ALMNAMAPTHDAC1HDAC2 | |
| SCHEMBL18667084 | 0.81 | KMT2A (0.47) | RAB9AMAPTHDAC1HDAC2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017048950-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2017-03-23 | — | — | WO | disclosed |