SCHEMBL186690

SCHEMBL186690

CC(C)(C)OC(=O)C(N)CO

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.38
NOS3 P29474 1/20 0.38
NOS2 P35228 1/20 0.38
LTA4H P09960 1/20 0.35
PRKCA P17252 1/20 0.34
SLC7A5 Q01650 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
DGAT1 O75907 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
SLC1A1 P43005 1/20 0.31
CYP3A4 P08684 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL918637 1.00 NOS1 (0.38) NOS1NOS3NOS2LTA4HPRKCA
SCHEMBL186691 1.00 NOS1 (0.38) NOS1NOS3NOS2LTA4HPRKCA
Hydrochloric Acid SCHEMBL918636 0.98 NOS1 (0.37) NOS1NOS3NOS2LTA4HPRKCA
Hydrochloric Acid SCHEMBL4555756 0.98 NOS1 (0.37) NOS1NOS3NOS2LTA4HPRKCA
Hydrochloric Acid SCHEMBL3104040 0.98 NOS1 (0.37) NOS1NOS3NOS2LTA4HPRKCA
Hydrochloric Acid SCHEMBL8601086 0.92 NOS1 (0.35) NOS1NOS3NOS2LTA4HPRKCA
SCHEMBL3294154 0.84 NOS1 (0.42) NOS1NOS3NOS2LTA4HSLC7A5
SCHEMBL569252 0.84 NOS1 (0.39) NOS1NOS3NOS2LTA4HSLC7A5
SCHEMBL5692825 0.84 DGAT1 (0.32) NOS1NOS3NOS2PRKCASLC7A5
SCHEMBL31295917 0.83 SLC7A5 (0.33) NOS1NOS3NOS2LTA4HSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119470406-A Phthalic dicarboxaldehyde disinfectant concentration detection test paper and preparation method thereof 山东新华莎罗雅生物技术有限公司 2025-02-18 CN claimed
CN-115108931-B Tofenamic acid derivative and preparation and application thereof 南华大学附属第一医院 2024-06-14 CN claimed
CN-117143145-A Preparation method of dioleoyl phosphatidylethanolamine 安徽昊帆生物有限公司 2023-12-01 CN claimed
CN-115108931-A Tofenamic acid derivative and preparation and application thereof 南华大学附属第一医院 2022-09-27 CN claimed
CN-112979935-B Mitochondrial targeting macromolecule carrier material TPP-PLA and fluorescein nanoparticles as well as preparation method and application thereof 湖北科技学院 2022-05-17 CN claimed
EP-3911795-A1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP Investments LLC (US) 2021-11-24 EP claimed
CN-112979935-A Mitochondrial targeting macromolecule carrier material TPP-PLA and fluorescein nanoparticles as well as preparation method and application thereof 湖北科技学院 2021-06-18 CN claimed
WO-2020150384-A1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2020-07-23 WO claimed
CN-106139159-B Application of polyethylene glycol derivative-small molecule drug conjugate polymer micelle in inflammation targeted drug delivery system 四川大学 2020-03-27 CN claimed
CN-109401511-A A kind of self-cleaning external wall of building water paint and preparation method 成都新柯力化工科技有限公司 2019-03-01 CN claimed
CN-107236073-A A kind of preparation method of antibacterial super branched polyacrylate optical liquid rubber 东莞市联洲知识产权运营管理有限公司 2017-10-10 CN claimed
CN-104055751-A Long-circulating and targeting synergistic multifunctional anti-tumor targeting nano-drug carrier UNIV NANKAI 2014-09-24 CN claimed
CN-102617503-B Novel synthetic method of (S)-3-morpholinyl carboxylic acid CHAINPHARM BIO MEDICAL CO LTD 2014-05-07 CN claimed
CN-101812014-B Amlodipine besylate compound and novel preparation method thereof MING WANG 2011-08-24 CN claimed
US-20250297149-A1 UNDERWATER ADHESIVE THE UNIVERSITY OF TOKYO (JP) 2025-09-25 US disclosed
CN-119613701-A Method for synthesizing functionalized polyether in multi-proton system 华南理工大学 2025-03-14 CN disclosed
CN-118255684-B CD4 enhancement+Compounds for T cell differentiation into Th9 cells 广州医科大学 2025-03-07 CN disclosed
WO-1995015979-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-15 WO disclosed
US-5254679-A Containing a quaternized nitrogen IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-10-19 US disclosed
EP-0347987-A2 Tripeptide renin inhibitors with N-terminal carbamoyl or acyl groups MERCK & CO. INC. (US) 1989-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250297149-A1 UNDERWATER ADHESIVE CDH1, EPCAM, ICAM1 NOS1 1348/4885NOS3 2582/4885NOS2 1219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.