SCHEMBL186691

SCHEMBL186691

CC(C)(C)OC(=O)[C@@H](N)CO

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.38
NOS3 P29474 1/20 0.38
NOS2 P35228 1/20 0.38
LTA4H P09960 1/20 0.35
PRKCA P17252 1/20 0.34
SLC7A5 Q01650 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
DGAT1 O75907 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
SLC1A1 P43005 1/20 0.31
CYP3A4 P08684 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL918637 1.00 NOS1 (0.38) NOS1NOS3NOS2LTA4HPRKCA
SCHEMBL186690 1.00 NOS1 (0.38) NOS1NOS3NOS2LTA4HPRKCA
Hydrochloric Acid SCHEMBL918636 0.98 NOS1 (0.37) NOS1NOS3NOS2LTA4HPRKCA
Hydrochloric Acid SCHEMBL4555756 0.98 NOS1 (0.37) NOS1NOS3NOS2LTA4HPRKCA
Hydrochloric Acid SCHEMBL3104040 0.98 NOS1 (0.37) NOS1NOS3NOS2LTA4HPRKCA
Hydrochloric Acid SCHEMBL8601086 0.92 NOS1 (0.35) NOS1NOS3NOS2LTA4HPRKCA
SCHEMBL3294154 0.84 NOS1 (0.42) NOS1NOS3NOS2LTA4HSLC7A5
SCHEMBL569252 0.84 NOS1 (0.39) NOS1NOS3NOS2LTA4HSLC7A5
SCHEMBL5692825 0.84 DGAT1 (0.32) NOS1NOS3NOS2PRKCASLC7A5
SCHEMBL31295917 0.83 SLC7A5 (0.33) NOS1NOS3NOS2LTA4HSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 714 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462826-B Pseudo peptide compound and preparation method and application thereof 成都普康唯新生物科技有限公司 2025-04-25 CN claimed
CN-119462826-A Pseudo peptide compound and preparation method and application thereof 成都普康唯新生物科技有限公司 2025-02-18 CN claimed
CN-119470406-A Phthalic dicarboxaldehyde disinfectant concentration detection test paper and preparation method thereof 山东新华莎罗雅生物技术有限公司 2025-02-18 CN claimed
CN-118239879-A Method for preparing 3-substituted oxindole, dihydroisoindigo and tetra-substituted ethane based on primary amine and application of primary amine 泰山学院 2024-06-25 CN claimed
CN-118005916-A Modified polyamino acid derivative with conformational regulating capability, preparation and application thereof 四川大学 2024-05-10 CN claimed
US-11332495-B2 Process for the preparation of Degarelix acetate and Degarelix acetate-mannitol premix RK Pharma Solutions LLC (US) 2022-05-17 US claimed
US-20210094984-A1 Process for the preparation of Degarelix acetate and Degarelix acetate-mannitol premix CITIBANK, N.A. 2021-04-01 US claimed
CN-102617503-B Novel synthetic method of (S)-3-morpholinyl carboxylic acid CHAINPHARM BIO MEDICAL CO LTD 2014-05-07 CN claimed
CN-103421088-A Solid-phase synthesis method for monocyte migration inhibitory factor GUANGDONG 8PLUS1 MEDICINE CO LTD 2013-12-04 CN claimed
CN-102617503-A Novel synthetic method of (S)-3-morpholinyl carboxylic acid CHAINPHARM CO LTD 2012-08-01 CN claimed
US-20250346578-A1 BIS(DIAZIRINE) DERIVATIVES AS PHOTO-CROSSSLINKER FOR TREATING CORNEAL ECTATIC DISORDERS AVEDRO INC (US) 2025-11-13 US disclosed
US-20250339388-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF MAXYMUNE THERAPEUTICS INC (US) 2025-11-06 US disclosed
US-20250319046-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF MAXYMUNE THERAPEUTICS INC (US) 2025-10-16 US disclosed
US-12427124-B1 Phenylalanine-based LAT1 inhibitors and uses thereof Maxymune Therapeutics, Inc. (US) 2025-09-30 US disclosed
US-12344598-B2 Bis(diazirine) derivatives as photo-crosslinker for treating corneal ectatic disorders AVEDRO, INC. (US) 2025-07-01 US disclosed
CN-1168673-A New dipeptide p-amidinobenzylamides with N-terminal sulfonyl or aminosulfonyl radicals BASF AG (DE) 1997-12-24 CN disclosed
EP-0733066-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1996-09-25 EP disclosed
WO-1995015979-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-15 WO disclosed
US-4656186-A FLUORESCENCE NIPPON PETROCHEMICALS CO., LTD. (JP) 1987-04-07 US disclosed
EP-0200218-A2 Tetrapyrrole therapeutic agents Nippon Petrochemicals Co., Ltd. (JP) 1986-11-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346578-A1 BIS(DIAZIRINE) DERIVATIVES AS PHOTO-CROSSSLINKER FOR TREATING CORNEAL ECTATIC DISORDERS SYMPK, DSG1, JUP NOS1 1028/4885NOS3 756/4885NOS2 595/4885
US-20250339388-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF SLC43A1, SLC7A1, SLC1A5 NOS1 1158/4885NOS3 2165/4885NOS2 1764/4885
US-11332495-B2 Process for the preparation of Degarelix acetate and Degarelix acetate-mannitol premix PEPD, DNPEP, PREP NOS1 2705/4885NOS3 2932/4885NOS2 2753/4885
US-20210094984-A1 Process for the preparation of Degarelix acetate and Degarelix acetate-mannitol premix PEPD, DNPEP, PREP NOS1 2731/4885NOS3 2948/4885NOS2 2779/4885
US-12427124-B1 Phenylalanine-based LAT1 inhibitors and uses thereof SLC43A1, SLC7A1, SLC1A5 NOS1 1158/4885NOS3 2165/4885NOS2 1764/4885
US-12344598-B2 Bis(diazirine) derivatives as photo-crosslinker for treating corneal ectatic disorders PSEN1, GRIK1, DSG1 NOS1 599/4885NOS3 1397/4885NOS2 866/4885
US-20250319046-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF SLC43A1, SLC7A1, SLC1A5 NOS1 1158/4885NOS3 2165/4885NOS2 1764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.